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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/30420
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dc.contributor.authorCobîleanschii, Eugeniu
dc.contributor.authorCobîleanscaia, Liubov
dc.date.accessioned2025-04-24T07:54:45Z
dc.date.available2025-04-24T07:54:45Z
dc.date.issued2025
dc.identifier.citationCOBÎLEANSCHII, Eugeniu and Liubov COBÎLEANSCAIA. The capacity of hepatic henodynamics in the nutritional assurance of hepatocytes in the elderly. In: Cells and tissues transplantation. Actualities and perspectives. The 3rd edition :  The Materials of the National Scientific Conference with international participation dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: [abstracts]. Chişinău: CEP Medicina, 2025, p. 79. ISBN 978-9975-82-413-2.en_US
dc.identifier.isbn978-9975-82-413-2
dc.identifier.urihttps://repository.usmf.md/handle/20.500.12710/30420
dc.description.abstractIntroduction. Blood supply to hepatocytes is severely compromised as a result of the difficult exchange of substances between hepatocytes and plasma, by the continuous deposition of collagen in the space of Disse, accompanied by the loss of fenestrations in the sinusoidal endothelial cells. The net result– fibrotic, nodular liver. The new vessels in the septa connect the vessels in the portal region (hepatic arteries and portal veins) and the terminal hepatic veins, altering blood flow. The purpose of the study consists in evaluation of indices of hepatic hemodynamic capacities in priority nutrient vessels in elderly patients with liver pathology. Material and methods. Hemodynamic parameters were studied by Doppler quantification in 32 patients: 18 men and 14 women with an average age of 69±0,21 years. The descriptive statistical test was applied. Results. The significant specificity and sensibility was demonstrated by changes in blood flow: decreased diastolic velocity (38%), increased volume velocity (57%) of the blood flow. The resistance index in the hepatic artery increased by 1,4%, the pulsatility index - by 6,3%, and the spatial velocity of the blood flow in the portal vein - by 7,7%. The spacial velocity oscillated between 990±69 ml/min and 1188±34 ml/min (approximately 20%). Conclusions. 1. The arterial vascularization’s sensitization implies heightened intraheptic vascular resistance amidst stagnant blood flow within the portal system in geriatric patients.en_US
dc.language.isoenen_US
dc.publisherCEP Medicinaen_US
dc.relation.ispartofCells and tissues transplantation. Actualities and perspectives. The 3-rd edition. Chisinau, March 21-22, 2025en_US
dc.subjectspace of Diseeen_US
dc.subjectDoppler quantificationen_US
dc.subjectdiastolic velocityen_US
dc.subjectvolume velocityen_US
dc.titleThe capacity of hepatic henodynamics in the nutritional assurance of hepatocytes in the elderlyen_US
dc.typeOtheren_US
Appears in Collections:The Materials of the National Scientific Conference with International Participation „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: [Abstracts]



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