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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/3190
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dc.contributor.authorHangan, Mariana
dc.contributor.authorCotelea, Tamara
dc.contributor.authorSoloviov, Larisa
dc.date.accessioned2019-06-25T01:54:35Z-
dc.date.available2019-06-25T01:54:35Z-
dc.date.issued2008
dc.identifier.citationHANGAN, Mariana, COTELEA, Tamara, SOLOVIOV, Larisa. Investigaţii chimico-toxicologice asupra metoclopramidei. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 9-a. Chișinău: CEP Medicina, 2008, vol. 1: Probleme medico-biologice şi farmaceutice, pp. 302-305.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/3190-
dc.descriptionCatedra Chimie farmaceutică şi toxicologică USMF “N.Testemiţanu” Centrul Ştiinţific in Domeniul Medicamentuluien_US
dc.description.abstractWe elaborated the TLC method of methoclopramide identification by using two developped systems, specrophotometric method of quantitative determination for methoclopramide in powder and tablets of 0.01g. Using the analytical methods elaborated by us over the artificial test there was extracted metoclopramide from biological liquids (plasma, urine). The output of methoclopramede from plasma was 50.44%; from urine- 46.80% Having considered the elaborated methods as specific and reproductive they are recommended for the study of methoclopramide in biological liquids. A fost elaborată metoda cromatografiei pe strat subţire de identificare a metoclopramidei, utilizând 2 sisteme de solvenţi,metoda spectrofotometrică de dozare în pulbere şi comrimate 0,01g. Aplicând metodele analitice elaborate de noi la probele biologice în „vitro” s-a efectuat extracţia metoclopramidei din lichidele biologice. Randamentul metoclopramidei din plasma sanguină este de 50,44%, din urină-46,80%. Dat fiind faptul, că metodele folosite sunt specifice şi reproductive ele se recomandă pentru studierea metoclpramidei în lichidele biologice.en_US
dc.language.isoroen_US
dc.publisherCEP "Medicina"en_US
dc.titleInvestigaţii chimico-toxicologice asupra metoclopramideien_US
dc.title.alternativeChemico-toxicological investigations on methoclopramideen_US
dc.typeArticleen_US
Appears in Collections:Chimie generală și farmaceutică

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