| DC Field | Value | Language |
| dc.contributor.author | Fandofan, Victoria | - |
| dc.contributor.author | Bozul, Uliana-Ariadna | - |
| dc.contributor.author | Jeru, Ion | - |
| dc.date.accessioned | 2026-04-07T07:49:23Z | - |
| dc.date.available | 2026-04-07T07:49:23Z | - |
| dc.date.issued | 2026 | - |
| dc.identifier.citation | FANDOFAN, Victoria; Uliana-Ariadna BOZUL and Ion JERU. Features of microsurgical treatment in patients with pterygium stage III.In: Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026. Chișinău: CEP Medicina, 2026, p. 98. ISBN 978-9975-82-477-4 (PDF). | en_US |
| dc.identifier.isbn | 978-9975-82-477-4 | - |
| dc.identifier.uri | https://repository.usmf.md/handle/20.500.12710/33086 | - |
| dc.description.abstract | Introduction:Pterygium is clinically manifested by a triangular fold of the bulbar conjunctiva with
the base towards the semilunar fold and the tip towards the cornea. The etiology and pathogenesis of
pterygium is unknown. It would result from a corneo-conjunctival epithelial alteration, associated with
a proliferation of fibrinogen tissue, progressing between the epithelium reduced to a few layers of cells
and the perforated Bowman's membrane.
Aim: To assess the effectiveness of a modified method in the treatment of pterygium,stage III.
Objectives:1. To determine the effectiveness of the modified method using the free conjunctival flap
plus subconjunctival administration of 5-FU (fluoruracil) in the treatment of patients with pterygium.
2. To appreciate the benefits of the modified method depending on the addressability of patients with
pterygium.
Materials and methods: The study included 8 patients (4 men and 4 women) with pterygium aged
20-71 years who underwent pterygium removal according to a modified method. Thus, during the
surgical intervention, a movable, free, rectangular flap with sides 5 x 3 mm was prepared inferiorly
paralimbally, which was fixed conjunctivally paralimbally, nasally in the area of the body of the
pterygium translocated to the superior or inferior fornix plus subconjunctival administration of 5-FU .
It is important to position the formed conjunctival flap with a limbal orientation.
Discussions: The postoperative recovery was fast, but for several days after the operation the globe
was hyperemic, irritating the suture fibers used to fix the conjunctival autograft. Antibiotic and antiinflammatory in the form of eye drops are needed. Thus, in all patients, 3 months after the
microsurgical intervention, no signs of recurrence of the operated pterygium were detected. In 2 latepresenting patients, the pterygium was extended onto the cornea, resulting in deep scarring. As a
consequence, the radius of corneal curvature was changed with the decrease in visual acuity in the
postoperative period. This is why surgery for pterygium should not have been delayed.
Conclusions: 1. The microsurgical method proposed for the treatment of pterygium is safe and
effective, determining the lack of recurrence in the postoperative period. 2. Microsurgical intervention
based on pterygium should be performed as early as possible. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | CEP Medicina | en_US |
| dc.relation.ispartof | Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026 | en_US |
| dc.subject | recurrent pterygium | en_US |
| dc.subject | free conjunctival flap | en_US |
| dc.subject | recurrence | en_US |
| dc.subject | postoperative period | en_US |
| dc.subject | 5-FU (fluoruracil) | en_US |
| dc.title | Features of microsurgical treatment in patients with pterygium stage III | en_US |
| dc.type | Other | en_US |
| Appears in Collections: | Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026
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