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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/3764
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dc.contributor.authorRevenco, Mircea
dc.contributor.authorNacu, Alexandru
dc.contributor.authorBoronin, Larisa
dc.contributor.authorNastas, Igor
dc.contributor.authorTrofailă, Eugen
dc.date.accessioned2019-06-25T09:43:31Z-
dc.date.available2019-06-25T09:43:31Z-
dc.date.issued2009
dc.identifier.citationREVENCO, Mircea, NACU, Alexandru. et al. Mecanisme patofiziologice în diskinezia tardivă. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 10-a. Chișinău: CEP Medicina, 2009, vol. 3: Probleme actuale în medicina internă, pp. 415-417.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/3764-
dc.descriptionCatedra Psihiatrie şi Narcologie FPM USMF „Nicolae Testemiţanu” IMSP Spitalul Clinic de Psihiatrieen_US
dc.description.abstractThe present work is a bibliographical revision of extrapyramidal reactions induced by neuroleptics. Clinical criteria a specified of late dyskinesia that appear after a long administration of neuroleptics, mainly after discontinuation of treatment with neuroleptics or diminishing of the dose, lack of efficacy, of muscarinic receptors of blockers. It is specified the paradoxal mechanism of late dyskinesia explained by increased susceptibility of dopaminic postsynaptic receptors from the stereopalidar area and the increasing of dopaminic synthesis as a response of tirozinhydroxilasis activity and of dopaminic metabolyts within spinal flaid. Lucrarea face o recapitulare bibliografică a reacţiilor extrapiramidale induse de neuroleptice. Sunt specificate criteriile clinice ale diskineziei tardive care apar după administrarea de durată a neurolepticelor, îndeosebi după anularea tratamentului cu neuroleptice sau scăderea dozei, lipsa de eficacitate blocanţilor de receptori muscarinici. Este specificat mecanismul paradoxal al diskineziei tardive explicat prin sensibilizarea crescută a receptorilor dopaminici postsinaptici din zona striopalidară şi creşterea sintezei dopaminei ca răspuns al activării tirozinhidroxilazei şi a metaboliţilor dopaminei în lichidul cefalorahidian.en_US
dc.language.isoroen_US
dc.publisherCEP "Medicina"en_US
dc.titleMecanisme patofiziologice în diskinezia tardivăen_US
dc.title.alternativePathophysiological mechanisms in late dyskinesiaen_US
dc.typeArticleen_US
Appears in Collections:Psihiatrie, narcologie

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