Aprecierea comparativă a efecienţei remediilor medicamentoase antianemice şi corelaţia dintre anemia fierodificitară şi patologia gastrică la copii

Abstract

Background: The problem of iron deficiency anemia in children is dependent on the evolution,of the pathology character, status of patients and particularities of each, but the most important are the therapeutic possibilities. Iron salts long period administration has resulted in a low percent of assimilation. Last clinical research and experimental studies have found new technologies and new antianemic drugs – Iron hydroxide with polymaltose or sucrose. Material and methods: The present study contains results of three antianemic remedies: Sorbifer Durules, Ferfol and Hemoglovit. The participants after screening were divided into three groups: 1. Group I – 32 children received Hemoglovit, 2. Group II – 18 children received Sorbifer Durules and the third group – 10 children received Ferfol. All the participants in the study have been investigated for gatsric pathology by two methods: fibrogastroduodenoscopy and gatsric biopsy. Results: Subjective and objective data were considerably improved after antianemic treatment. Peripheral blood indices were reestablished the same after all three drugs. We have ascertained a pathogenic mechanism of gastric pathology influence on anemia evolution. Conclusions: One of the anemia causes is the lack of an efficient treatment of functional as well as morphological changes that occur in the digestive tract.