Improvement of onychomycoses treatment using the agents which optimize the structure of nail plate and its growth

Abstract

Background: Onychomycosis is one of the current medico-social challenges. The article deals with the advantages of combined comprehensive therapy rendered to patients with onychomycoses using systemic antimycotics and vitamin agent Wolvit over standard therapeutic regimen determined by a comparative study of two groups. Material and methods: We observed 43 patients with onychomycosis of hands and feet: the main group (33 patients) received Wolvit 5 mg per day and systemic antimycotic in standard dosage, control group (10 persons) – systemic antimycotic. The course of treatment was 1.5 months for onychomycosis of the hands and 3 months for onychomycosis of the feet. All patients underwent a comprehensive clinical and laboratory examination. Mycological research was on the fourth, sixth, eighth, tenth, twelfth and sixteenth weeks of treatment. Results: The administration of vitamin agent Wolvit together with systemic antimycotics allows to achieve a significant improvement of nail plate structure as it acquires even light pink translucent color, glossy surface, smooth and thick free edge, normotrophic structure. Participation of biothinum in the formation of keratine, necessary for the development of hair matrix and nail plate, results in acceleration of healthy nail growth in patients with onychomycoses. Biothinum is also a source of sulphur, which transports sulphur into the skin and its accessory organs, contributing to collagen formation and therefore eliminates signs of early hair depigmantation, normalizes sebaceous glands function and exerts a positive impact on the structure of skin and its accessory organs (hair, nails). Conclusions: The obtained results show that the developed complex is effective, safe and allows to achieve both clinical and etiologic recovery