Metodă de tratament al hepatitei virale C la copiii cu contraindicăţii la tratamentul standard antiviral

Abstract

The purpose of the work consists in obtaining the methods of treatment of chronic viral hepatitis C even in a situation when the patients have contraindications to the administration of standard antiviral therapy, and in improving the biochemical parameters and reducing the duration of hospitalization of the children with chronic viral hepatitis C. The presented materials demonstrate the effectiveness of an original method of treatment of viral hepatitis C in the case of high cytolysis associated with unbalanced diabetes, renal decompensation, non-viral autoimmune diseases, epilepsy and other diseases, which have contraindications to the administration of antiviral therapy. The basic therapy has been supplemented by the national phytopreparation Pacovirin in capsules with antiviral, immunomodulatory, antioxidant and interferonogenic activity. The efficacy of Pacovirin has been assessed on the basis of clinical, virological, immunological and biochemical indices. At the same time the analysis and evaluation of the results in the context of modern literature sources concerning the treatment of chronic hepatitis C in children with contraindications to standard antiviral therapy has been performed. The obtained results demonstrate an increased effectiveness of the treatment that is manifested by more rapid normalization of clinical and laboratory indices.