Особенности гемодинамики при хронической обструктивной болезни легких

Abstract

Clinical and morpho-functional changes of the cardio-vascular system were studied in 75 patients with chronic obstructive pulmonary disease (COPD) of all three stages, which were compared with the changes in healthy persons and patients with myocardial ischemia (MI). It was established that in patients with COPD the thickness of the right ventricle walls measured 5.05±1.18 mm, higher than in healthy subjects and patients with MI whose FDPLV measured 27.65±4.25 mm, also higher than in healthy persons and patients with MI. In addition, there was a more significant thickening of the RVM and PWLV in comparison with the control groups. In patients with COPD there was observed RWT, LVMM and LVMMI in comparison with the control lots, establishing a process of myocardial remodeling of the LV in association with diastolic dysfunction of the RV.

La 75 de pacienţi cu bronhopneumopatie cronică obstructivă (BPCO) au fost studiate modificările clinice şi morfo-funcţionale ale sistemului cardio-vascular în funcţie de stadiul bolii. A fost stabilit că la, pacienţii cu BPCO, grosimea pereţilor VS constiuia 5,05±1,18 mm şi era veridic mai mare decât indicii atestaţi la bolnavi cu BIM, PDFVS constituia 27,65±4,25 mm şi era veridic mai înaltă decât la persoanele sănătoase şi pacienţii cu BIM. De asemenea, s-a înregistrat majorarea veridică a grosimii MVD şi a PPVS, în comparaţie cu datele cercetaţilor din loturile de control. La bolnavii cu BPCO s-a depistat majorarea veridică a GRP, MMVS şi IMMVS, în comparaţie cu indicii loturilor de control, ceea ce indică prezenţa remodelării concentrice a miocardului VS cu dezvoltarea disfuncţiei diastolice a ventriculelor drept şi stâng.