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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/9938
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dc.contributor.authorKazimli, Firuza
dc.date.accessioned2020-05-27T15:15:02Z
dc.date.available2020-05-27T15:15:02Z
dc.date.issued2018
dc.identifier.citationKAZIMLI, Firuza. The role of brain MRI in mesial temporal lobe epilepsy. In: The Moldovan Medical Journal. 2018, vol. 61, RMI Congress Issue, p. 95. ISSN 2537-6381.
dc.identifier.issn2537-6373
dc.identifier.issn2537-6381 (Online)
dc.identifier.urihttp://moldmedjournal.md/wp-content/uploads/2018/05/The-Moldovan-Medical-Journal-vol-61-mai.pdf
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/9938
dc.descriptionDepartment of Radiology and Imaging, Nicolae Testemitsanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova, The IVth Congress of Radiology and Medical Imaging of the Republic of Moldova with international participation, Chisinau, May 31 – June 2, 2018en_US
dc.description.abstractBackground: Mesial temporal lobe epilepsy is the most common form of epilepsy. Since its pathophysiological substrate is usually related to hippocampal sclerosis, the seizures are typically resistant to antiepileptic drugs and surgical treatment is considered in most patients. Defining the affected region on medical imaging is of paramount importance in this situation. The study aimed to evaluate the role of brain magnetic resonance imaging (MRI) in patients with suspected mesial temporal lobe epilepsy and its ability to reveal the responsible epileptogenic focus. Material and methods: The study included 96 patients aged 3 to 48 years old with clinical suspicion of temporal lobe epilepsy who underwent a brain MRI scan at the Medpark International Hospital in the period 25.01.2017 – 25.01.2018. The scans were performed on a Siemens Essenza 1.5 Tesla MRI scanner using a specially designed epilepsy imaging protocol (sag T1W, T2W, T2-tirm, DWI). Additional sequences (such as cor T2 FLAIR, T1 IR + contrast) were also included if required. Results: From a total of 96 patients, brain MRI revealed the potential epileptogenic region in 27 (28%) cases. The MRI findings in these patients included increased signal intensity in the region of hippocampus (23 patients), hippocampal atrophy or volume loss (19 patients), enlarged temporal horn (11 patients), smaller temporal lobe (10 patients) and collateral white matter atrophy (6 patients). Conclusions: In our study, mesial temporal sclerosis was the most common identifiable cause of seizures. Even though brain MRI features may vary, the increased hippocampal signal intensity was the most consistent finding.en_US
dc.language.isoenen_US
dc.publisherThe Scientific Medical Association of the Republic of Moldovaen_US
dc.relation.ispartofThe Moldovan Medical Journal: The IVth Congress of Radiology and Medical Imaging of the Republic of Moldova with international participation, Chisinau, May 31 – June 2, 2018
dc.subjectMRIen_US
dc.subjectmesial temporal epilepsyen_US
dc.subjectmesial temporal sclerosisen_US
dc.titleThe role of brain MRI in mesial temporal lobe epilepsyen_US
dc.typeOtheren_US
Appears in Collections:The Moldovan Medical Journal, Vol. 61, May 2018 RMI Congress Issue

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