Issue dedicated to the 75th anniversary of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova (1945-2020) http://repository.usmf.md:80/xmlui/handle/20.500.12710/12301 2026-04-12T20:59:42Z 2026-04-12T20:59:42Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/16914 2021-09-22T14:45:18Z 2020-01-01T00:00:00Z

The Moldovan Medical Journal. December 2020, Vol. 63, No 6 The Moldovan Medical Journal is an international scientific double-blind peer-reviewed periodical edition, 4 per year, of the Scientific Medical Association of the Republic of Moldova designed for specialists in the areas of medicine, dentistry, pharmacy, social medicine, and public health. From its debut, the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The Editorial Board warmly welcomes both the readers of and the authors of the journal, all those who are enthusiastic about searching for new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution to the science of medicine will find our journal helpful and encouraging. The 75th anniversary of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova (1945-2020). Founder: The Scientific Medical Association of the Republic of Moldova

2020-01-01T00:00:00Z Placinta, Gheorghe Vorojbit, Valentina Pantea, Victor Cojuhari, Lilia Cebotarescu, Valentin Placinta, Lidia Croitoru, Dan http://repository.usmf.md:80/xmlui/handle/20.500.12710/15265 2021-09-23T07:37:38Z 2020-01-01T00:00:00Z

Clostridium difficile infection in the intensive care unit Placinta, Gheorghe; Vorojbit, Valentina; Pantea, Victor; Cojuhari, Lilia; Cebotarescu, Valentin; Placinta, Lidia; Croitoru, Dan Abstract Background: Clostridium difficile (CD) infection is widespread throughout the world, showing an increased incidence over the recent years and may cause severe forms of disease. This infection most commonly affects patients whom were administered antibiotics. An increased resistance to commonly used antibiotics is associated with Clostridium difficile infection (CDI). CD has a generally recognized infectious potential on a clinical ground. CDI is unpleasant and may sometimes cause serious bowel disorders that are usually treated with another course of antibiotics. The evolution of CD infection depends on the individual characteristics of the patient along with risk factors, associated diseases as well as the particularities of the recommended treatment. However, even under the conditions of a correct and complete treatment the risk of the disease relapse is estimated to occur depending on risk factors. Many clinical instruments that are designated for the purposes to treat non-infectious diseases can be useful in estimating the severity of an infection. This review is important for understanding the abusive and irrational prescription of various groups of antibiotics, often unjustified, including the ones used in the treatment of an infection with SARS-CoV-2. Conclusions: These infections mostly occur in people aged 65 and older that receive medical care, including antibiotics administration, people with a long-term hospital stay, people with a weakened immune system or with a previous CD infection. The following measures, in order to reduce the risk of CDI in patients, should be considered: hand hygiene, avoidance of unnecessary administration of antibiotics – the antibiotic treatment is recommended only if it is prescribed by an experienced specialist, avoidance of unnecessary administration of drugs that reduce gastric acidity, because it favors the invasion of the gastrointestinal tract with CD.

2020-01-01T00:00:00Z Doten, Natalia http://repository.usmf.md:80/xmlui/handle/20.500.12710/12322 2021-09-23T07:21:36Z 2020-01-01T00:00:00Z

Presurgical and postsurgical neuropsychological assessment in epilepsy Doten, Natalia Background: Epilepsy surgery represents a valuable treatment for people with drug-resistant epilepsy, which often leads to a substantial improvement in the cognitive-behavioral domains and to a better quality of life, especially in children. A neuropsychological assessment is considered mandatory and should form an integral component of the presurgical evaluation and assessment of postoperative outcome for all epilepsy surgery patients. In this context, the presurgical neuropsychological assessment in combination, as well as other relevant neurological investigations are important for assessing the risk of potential postsurgical cognitive deficits, to determine the dominant hemisphere responsible for language function and to predict the risk of memory decline and of visual and motor deficits. A postsurgical neuropsychological assessment is necessary in assessing the outcomes because cognitive decline is one of the most significant sequelae of epilepsy surgery. Conclusions: The neuropsychological assessment remains an obligatory and valuable part of the presurgical and postsurgical assessment. This article provides a comprehensive overview of the role of neuropsychological assessment in the pre- and postsurgical evaluation of epilepsy surgery patients. The neuropsychological profile may have a predictive role for the identification of the cognitive risk, prognosis, and treatment. New researches about neuropsychological assessment may provide many relevant answers about the outcome of the epilepsy surgery as well as to influence the quality of life. Neurobiology and Medical Genetics Laboratory, National Center of Epileptology, Institute of Emergency Medicine, Department of Neurology No 2, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova. The 75th anniversary of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova (1945-2020)

2020-01-01T00:00:00Z Condratiuc, Elena http://repository.usmf.md:80/xmlui/handle/20.500.12710/12321 2021-09-23T07:22:04Z 2020-01-01T00:00:00Z

The psychotherapeutic aspect of psychic trauma in epilepsy Condratiuc, Elena Background: The management of epilepsy can be reviewed in a multidimensional way, medical, psychotherapeutic, familial and social. In this regard, we are talking about the position given to the patient suffering from epilepsy.From a psychopathological point of view, there is a system of interactions between crisis and personality based on confusional anxieties, related to ambiguity and the feeling of crisis for the subject. The psychotherapeutic understanding of the patient suffering from epilepsy is situated in a bio-psycho-familial and social context. Whether it is the first, the second, or the next crises, they point out that there is an intrapsychic trauma. Conclusions: System of interactions between epilepsy, the patient and the environment contributes to the creation of the framework that will provide opportunities to help the patient. Psychotherapy sessions allow the patient to reintroduce the crisis in his history. The description of psychological experiences that are associated with the evolution of epilepsy symptoms, will allow us to form an idea about the influence of psychic trauma on the clinic and the dynamics of epilepsy, which could help identify an approach to the patient’s adaptation. Department of Neurology, National Center for Epileptology, Institute of Emergency Medicine, Laboratory of Neurobiology and Medical Genetics, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova. The 75th anniversary of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova (1945-2020)

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