http://repository.usmf.md:80/xmlui/handle/20.500.12710/14604 2026-04-12T07:14:09Z 2026-04-12T07:14:09Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/16664 2023-01-25T10:30:04Z 2021-01-01T00:00:00Z

One Health & Risk Management. 2021, Vol. 2 No 1 One Health & Risk Management is a biannual scientific journal for specialists in medical and biological sciences, which was founded in 2019 within the Moldavian Biosafety and Biosecurity Association (MDBBA). The journal accepts submissions in Romanian, English, French and Russian, in accordance with current international standards and guidelines. The Journal policy is aligned with the new concepts of international organizations (WHO, OIE FAO, etc.), such as One Health Approach, enclosed within a cooperative, multisectoral, transdisciplinary, national and international framework. The current state of the contemporary world in terms of depth and dynamics of changes, as well as the accelerated rate of research and innovation on evidence-based risk management, generate a progressive growth in the amount of medical and biological data. Therefore, One Health & Risk Management Journal will support and publish manuscripts based on scientific evidence on human, animal and environmental health. The priority for acceptance would be given to those articles which report study results on identification of specific hazards and risk assessment associated with these hazards, development and analysis of potential risk management options, as well as selection and implementation of a specific monitoring and evaluation strategy used for risk management. The rigorous review process (double-blind peer review) will involve professionals from various scientific fields, who comply with the international ethical guidelines for scientific publications. One Health & Risk Management magazine will increase its visibility by exchanging articles with other relevant publications and collaborating with similar national and international organizations, as well as via its website, which includes the recently published articles, providing the opportunity to get real-time information (Free Open Access). The editorial board of the magazine brings together outstanding personalities, both from the country and abroad, who help to maintain the journal to the highest scientific standards. Fondator: Asociația de Biosiguranță și Biosecuritate din Republica Moldova

2021-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/14828 2021-01-07T16:04:44Z 2021-01-01T00:00:00Z

Mihail Magdei – ilustru medic, manager și savant în sănătate publică!

2021-01-01T00:00:00Z Novossiolova, Tatyana Perkins, Dana http://repository.usmf.md:80/xmlui/handle/20.500.12710/14827 2021-01-07T15:59:41Z 2021-01-01T00:00:00Z

Life sciences professional responsibility in an age of dual-use research Novossiolova, Tatyana; Perkins, Dana INTRODUCTION Biotechnology is progressing at an unprecedented pace promising to bring tremendous benefits by responding to health, socio-economic, and environmental challenges. At the same time, cutting-edge life sciences advances raise multifaceted social, legal, ethical, and security concerns, including the risk of accidental or deliberate misuse. Reconciling the expected benefits with potential risks requires effective governance of dual-use life science research. The US National Science Advisory Board for Biosecurity (NSABB), a consultative committee to the US Government defines ‘dual-use research’ as “the development of new technologies and the generation of information with the potential for benevolent and malevolent purposes” noting that “virtually all life sciences research has dual use potential” (1). To facilitate policy-making in this area at national as well as institutional level, the NSABB has developed a criterion for identifying dual-use research of concern (DURC): “life sciences research that, based on current understanding, can be reasonably anticipated to provide knowledge, information, products, or technologies that could be directly misapplied to pose a significant threat with broad potential consequences to public health and safety, agricultural crops and other plants, animals, the environment, materiel, or national security” (2, 3). Dual-use risk management needs to be multi-layered and flexible; regulation per se is not sufficient to capture the wide-ranging security implications of cutting-edge life science advances. Fostering a shared understanding within the life science community of the risk that the life sciences could be misused in ways that cause harm to humans, animals, or plants is key. Life sciences stakeholders have a duty to be aware of the potential for misuse of scientific findings and of their obligation to help inform and shape critical policy decisions about biological security in the life sciences (1).On the other hand, policymakers should also seek to strike an appropriate balance between national security and unhindered scientific research when considering DURC governance options.

2021-01-01T00:00:00Z Tcaciuc, Eugen Podurean, Mariana Schiopu, Olga Batrinac, Aurel Selivanov, Angela Coloman, Dumitru http://repository.usmf.md:80/xmlui/handle/20.500.12710/14826 2021-01-08T12:05:34Z 2021-01-01T00:00:00Z

Case report: acute liver failure induced by Paracetamol toxicity Tcaciuc, Eugen; Podurean, Mariana; Schiopu, Olga; Batrinac, Aurel; Selivanov, Angela; Coloman, Dumitru Introduction Paracetamol is the most commonly used drug across Western Europe and North America. There is no such trend of using Paracetamol in the Republic of Moldova, thus overdose cases are extremely rare. The mechanisms leading to overdose episodes might induce hepatotoxicity. Clinical case This present article reports a case of acute liver failure induced by Paracetamol overdose. A 46-year-old man presented to the Medpark International Hospital. He was administered Paracetamol 1000 mg, approximately every 4 hours for 2 days, and 1000 mg twice a day for another 2 days, after an intense physical exertion, followed by muscle fever with myalgia and low-grade fever (37.4 °C) The reason for asking the medical care were pronounced fatigue, nausea, loss of appetite, night sweats, and frequent urination. Conclusion Eventually, the case was successfully resolved due to N-acetyl-cysteine, administered according to the established treatment scheme, as well as the adjuvant therapy.; Paracetamolul este cel mai frecvent utilizat medicament în Europa de Vest și America de Nord. În Republica Moldova nu există, însă, această tendință și în consecință, cazuri de supradozaj înregistrate se atestă foarte rar. Mecanismele ce se derulează în timpul episoadelor de supradozaj induc hepatotoxicitate. Cazul clinic În acest articol relatăm un caz de insuficiență hepatică acută indusă de supradozajul cu Paracetamol. Un bărbat de 46 ani s-a adresat la Spitalul Internațional Medpark, care în urma unui efort fizic intens, ce a cauzat febră musculară cu mialgii și subfebrilitate (37,4°C), a administrat comprimate Paracetamol, 1000 mg aproximativ la fiecare 4 ore 2 zile, după care câte 1000 mg de 2 ori pe zi încă 2 zile. Ulterior au apărut simptome de fatigabilitate pronunțată, grețuri, inapetență, transpirații nocturne și micțiuni frecvente, acestea fiind motivul solicitării ajutorului medical. Concluzii Datorită medicației cu N-acetilcisteină, aplicată conform schemei de administrare instituite, cât și a tratamentului adjuvant, cazul respectiv a fost soluționat cu succes.

2021-01-01T00:00:00Z