Curierul Medical, 2016, Vol. 59, No 6

Curierul medical. December 2016, Vol. 59, No 6

2016-01-01T00:00:00Z

Curierul medical. December 2016, Vol. 59, No 6 From its debut in 1958, the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The Editorial Board warmly welcomes both the readers of and the authors for the journal, all those who are enthusiastic in searching the new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution into the science of medicine will find our journal helpful and encouraging. The journal is accredited by the National Council for Accreditation and Attestation. The journal publishes official papers, scientific articles, editorials, clinical studies and cases, lectures, methodological guides, reviews, brief reports, and correspondence. The journal welcomes articles in English, Romanian and Russian. The journal editorial policy provides the prompt publication of papers within 12 weeks after receiving them.; De la prima apariţie în 1958, revista susţine şi dezvoltă noile idei în domeniul medicinii, în Republica Moldova. Colegiul de redacţie agrează cu multă consideraţie atât cititorii cât şi autorii articolelor, pe toţi acei care cu mult entuziasm caută noi şi mult mai efective metode de soluţionare a multiplelor probleme ale medicinii. Sperăm, că toţi acei care doresc să-şi aducă aportul la dezvoltarea ştiinţelor medicale, vor găsi revista noastră utilă şi atractivă. Revista este acreditată de către Consiliul Naţional de Acreditare și Atestare. Revista publică comunicări oficiale și, totodată, sunt editate diverse publicaţii, inclusiv independente: articole știinţifice, editoriale, cercetări și prezentări de cazuri clinice, prelegeri, îndrumări metodice, articole de sinteză, relatări scurte, corespondenţe și recenzii. Revista publică articole în limba engleză, română și rusă. Politica de editare a revistei prevede examinarea operativă și publicarea articolelor timp de 12 săptămâni după înaintare.; С первого дня своего выпуска в 1958 году журнал стремится поддерживать и развивать новые идеи в области медицины в Молдове. Редакционная коллегия всегда рада как читателям, так и авторам статей, всем тем, кто с энтузиазмом ищет новые, более эффективные способы решения многочисленных задач медицины. Мы надеемся, что все те, кто хотят внести свой вклад в медицинскую науку, найдут наш журнал полезным и вдохновляющим. Журнал аккредитован Высшей Аттестационной Комиссией Республики Молдова. В журнале печатаются официальные материалы, научные статьи, наблюдения из клинической практики, обобщающие статьи, краткие сообщения, методические указания, рецензии и корреспонденция. В журнале публикуются статьи на английском, румынском и русском языках. Издательская политика журнала предусматривает оперативное рассмотрение и публикацию статей в среднем в течение 12 недель после поступления. Fondatori: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu”

Impact of primary health care sector in the detection of tuberculosis on the model of Chisinau city

2016-01-01T00:00:00Z

Impact of primary health care sector in the detection of tuberculosis on the model of Chisinau city Lesnic, Evelina; Niguleanu, Adriana; Ganta, Ana; Jucov, Artiom; Nintus, Raisa; Curocichin, Ghenadie Background: Tuberculosis detection represents the major challenge in actual health care system, recognised in the Republic of Moldova and worldwide. Material and methods: 101 pulmonary TB patients diagnosed in the period 1.1.2015-31.12.2015 in Chisinau were enrolled and distributed into two groups: the 1st group consisted of 73 patients with pulmonary TB detected in the frame of primary health care sector by general practitioners as symptomatic patients, and the 2nd group consisted of 28 patients with pulmonary TB detected by general practitioners by active way of screening. Results: Patients from both groups were enrolled in a similar proportion according to the demographic characteristics (urban/rural residency, civil and educational status). Two thirds of both groups were uninsured, but the economic state was lower in the group of patients detected as symptomatic cases. Chronic alcoholism, drug use, history of imprisonment, migration, comorbidities were established in a similar number of cases from both groups. Despite the fact that high risk groups (TB contacts and HIV infected individuals) must be screened actively, their rate is statistically higher in the group detected by passive way. Smear positive results, extensive pulmonary infiltrates and lung parenchyma destructions predominated in the group detected by passive way. The rate of patients that successfully finished the treatment was similar in both groups, but deaths were registered only in the group detected by passive way. Conclusions: The Republic of Moldova registers a continuous decrease of epidemiological TB indices due to the reduction of high risk groups designed to be investigated and the insufficient use of active screening.

Inflammatory pathologies of genitalia in girls and adolescents

2016-01-01T00:00:00Z

Inflammatory pathologies of genitalia in girls and adolescents Profire, Liliana Background: Children and adolescents are a group of population that represents 1/3 of territorial population with specific biological peculiarities of age, activity, health and morbidity. Professional medical assistance given to the young generation ensures for subsequent generations a nice and healthy future. Material and methods: The present study is non-experimental, of a descriptive type with a general group of 400 patients hospitalized during 2014 in the department of pediatric gynecology. Statistical processing was performed using the program «Epiinfo 2002» and the program « Microsoft Office Excel 2010». Results: According to the obtained results within the study the inflammatory diseases of genitals were most frequently diagnosed – 263 cases (65.8±2.37%), the majority of which 254 (96.6 ±1.11%) of a non-specific genesis and 9 cases (3.4±1.11%) bacterial infections of specific genesis, P<0.001. In half of the investigated cases 108 (52.7±3.48%) there have been cultivated combinations of pathogens, the most frequently determined being: E. coli+corinebacterium, E. coli+corinebacterium +Enterococcus fecalis, or Corinebacterium + St. Viridans, Streptoccoccus saprophyticus+corinebacterium. From the total number of non-specific inflammatory diseases prevail inflammatory diseases of external and inferior internal genitals 169 (66.5±2.96%), P<0.001 – vulvovaginitys: acute vulvovaginitys, chronic relapsing vulvovaginitys with a maximum share in the age group 1-4 years old 68 (40.2±3.79%). Contrary to the distribution of inflammatory diseases of the inferior and external genital tract, the inflammatory diseases of the upper genitals increase with the advancement in age of the patients involved in the study with a maximum rate in the group of adolescents of 16-19 years old (55.4±5.47%), P<0.001. Conclusions: An increase of the inflammatory processes of genitals in the age groups 1-4 (22.3%) and 16-19 (25.8%) was determined. A maximum share of inflammatory diseases of inferior genitals was determined in patients aged 1-7 and inflammatory diseases of the upper genital tract in the period of adolescence – 14-19 years old.

The essence of the cell therapy method in chronic ischemia of the lower limb

2016-01-01T00:00:00Z

The essence of the cell therapy method in chronic ischemia of the lower limb Visnevschi, Sergiu Background: The results of the of cell therapy use in experimental models of ischemia of the lower limbs, in the majority of cases performed on mice and rats, and also on bigger animals demonstrated the possibilities and effectiveness of cell therapy in restoring blood flow to ischemic regions of the member. The third important property of stem cells is that they can be differentiated into diverse specialized cell types, such as muscle cells, endothelial, nervous, etc. Stem cells are the basic unit of the body, from them are formed 240 types of specialized cells and tissues of the body. These cells are involved in the revascularization and increase the secretion of numerous pro-angiogenic factors (VEGF, bFGF, PlGF-1 and MCP-1). All preclinical studies demonstrate a local neovascularization, with a functional effect, particularly in the form of increased blood flow and the number of newly formed vessels. Aspects and perspectives of cell therapy in the treatment of chronic peripheral angiopathy, especially on lower limbs are considered in this work. Conclusions: Angiogenic cell therapy today provides a therapeutic method and also an innovation that represents a breakthrough concept in treatment of ischemic diseases, especially of the legs and heart, the improvement of prognosis of these patients. This method comes to substitute the conventional methods of treatment of these diseases, which until now claim to be less effective or even ineffective, and simultaneously takes an important step in the progress of therapy, which further enriches the arsenal of methods of medical treatment. Cell therapy is one of the most perspective methods of treatment at the current stage, with the use of mature autologous mesenchymal cells, in order to increase the number of capillaries (angiogenesis), and larger caliber vessels (vasculogenesis).