http://repository.usmf.md:80/xmlui/handle/20.500.12710/1130 Fri, 01 May 2026 19:17:44 GMT 2026-05-01T19:17:44Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/16197 Curierul medical. August 2016, Vol. 59, No 4 From its debut in 1958, the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The Editorial Board warmly welcomes both the readers of and the authors for the journal, all those who are enthusiastic in searching the new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution into the science of medicine will find our journal helpful and encouraging. The journal is accredited by the National Council for Accreditation and Attestation. The journal publishes official papers, scientific articles, editorials, clinical studies and cases, lectures, methodological guides, reviews, brief reports, and correspondence. The journal welcomes articles in English, Romanian and Russian. The journal editorial policy provides the prompt publication of papers within 12 weeks after receiving them.; De la prima apariţie în 1958, revista susţine şi dezvoltă noile idei în domeniul medicinii, în Republica Moldova. Colegiul de redacţie agrează cu multă consideraţie atât cititorii cât şi autorii articolelor, pe toţi acei care cu mult entuziasm caută noi şi mult mai efective metode de soluţionare a multiplelor probleme ale medicinii. Sperăm, că toţi acei care doresc să-şi aducă aportul la dezvoltarea ştiinţelor medicale, vor găsi revista noastră utilă şi atractivă. Revista este acreditată de către Consiliul Naţional de Acreditare și Atestare. Revista publică comunicări oficiale și, totodată, sunt editate diverse publicaţii, inclusiv independente: articole știinţifice, editoriale, cercetări și prezentări de cazuri clinice, prelegeri, îndrumări metodice, articole de sinteză, relatări scurte, corespondenţe și recenzii. Revista publică articole în limba engleză, română și rusă. Politica de editare a revistei prevede examinarea operativă și publicarea articolelor timp de 12 săptămâni după înaintare.; С первого дня своего выпуска в 1958 году журнал стремится поддерживать и развивать новые идеи в области медицины в Молдове. Редакционная коллегия всегда рада как читателям, так и авторам статей, всем тем, кто с энтузиазмом ищет новые, более эффективные способы решения многочисленных задач медицины. Мы надеемся, что все те, кто хотят внести свой вклад в медицинскую науку, найдут наш журнал полезным и вдохновляющим. Журнал аккредитован Высшей Аттестационной Комиссией Республики Молдова. В журнале печатаются официальные материалы, научные статьи, наблюдения из клинической практики, обобщающие статьи, краткие сообщения, методические указания, рецензии и корреспонденция. В журнале публикуются статьи на английском, румынском и русском языках. Издательская политика журнала предусматривает оперативное рассмотрение и публикацию статей в среднем в течение 12 недель после поступления. Fondatori: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu” Fri, 01 Jan 2016 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/16197 2016-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/2939 Segregation of tuberculosis patients by social, demographic and economic features on the model of Chisinau city and the role of community support Lesnic, Evelina; Paladi, Carmina; Niguleanu, Adriana; Ciubotaru, Viorica; Sirbu, Petru; Curocichin, Ghenadie Background: One of the most important actions in tuberculosis control represents the improvement of social and economic conditions, as well as nutrition, hygiene, housing and working state of the population. Commission on Social determinants of Health suggests to all tuberculosis burden countries, especially targeting research sector, governments and academia institutions to implement health-oriented interventions, as being the most powerful potential efforts in tuberculosis control. The aim of the study was the segregation of tuberculosis patients according to the social, demographic and economic characteristics revealed at the regional level in Chisinau city for identifying target groups for improving the earlier case-detection. Material and methods: 185 pulmonary tuberculosis patients diagnosed in the period 01.01.2015-31.12.2015 in Chisinau city were investigated. Results: While segregating new cases of pulmonary tuberculosis there were identified several high risk groups for active disease: social risk groups with specific features – uninsured, unemployed, living in poor conditions; groups with suppressing medical conditions; epidemiologically endangered groups – homeless, migrants and contacts with tuberculosis patients; persons with harmful habits (alcohol abusers, injection drug users). Due to enumerated risk factors it was identified that one half of patients were late detected as being microscopic positive for acid-fast-bacilli that presented the highest epidemiological danger. Conclusions: Social and community support must take into account the segregation of TB patients method for improving awareness, education and information of high risk groups and specific groups for tuberculosis. Fri, 01 Jan 2016 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/2939 2016-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/2940 The use of medical ozone in dentistry Pirgari, Andrei Background: Lately, due to a higher incidence rate of infections, as a result of a decreased immuno-inflammatory response capacity of the human body and an expanded role of viral agents in triggering inflammatory diseases, the interest for the use of medical ozone has increased significantly. The reason for this growth of popularity lies in the fact that medical ozone has antimicrobial, antiviral, anti-inflammatory, immunomodulatory, antioxidant and other properties; it is not a pharmacological product, but rather a “hormetic stress” [18], a pure ecologic physico-chemical factor with multiple biological effects [19]. Conclusions: The action of medical ozone on the human body is diverse and multidirectional. The pharmacological effect of medical ozone represents the so-called “hormesis” phenomenon, and this effect is triggered by short chains of hydroxides – hydro-peroxides, also defined as ozone peroxides. Medical ozone possesses antalgic, anti-inflammatory, anti-edematous, antioxidant, myorelaxant, detoxing, immunomodulatory, antimicrobial, antiviral, antifungal effects, it activates the cellular metabolic processes, stimulates oxygen metabolism and improves rheological properties of blood. In dentistry, medical ozone is used on its own or in combination with other treatment methods. At the same time, the aspects of the use of medical ozone in clinical periodontology requires additional research. Fri, 01 Jan 2016 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/2940 2016-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/2933 Comparative clinical study of depigmentation products on facial melasma in Latin women Orlandi-Jorquera, Cecilia; Moran-Cardenas, María Gabriela; Escobar-Huenchul, Valery Magdalena Background: Hyperpigmented lesions need the most frequent dermatological consultations, the acquired ones being more effectively treated. Out of them, the most common is melasma, which is currently treated with hydroquinone. Our objective was to compare the efficacy of a treatment based on Diacetylboldine-DAB, Alpha arbutin and Licorice with hydroquinone 4%. Material and methods: We carried out a pilot study on 30 Latin patients (skin type III and IV after Fitzpatrick’s classification). The product under study was applied on one side of the face and hydroquinone on the other, during 60 days. Results: The study product demonstrated effectiveness comparable to 4% hydroquinone in the 60 days of monitoring time. The hyperpigmentations are of a chronic type and so, considering the formula of the study product, it has the great advantage of permitting use for a prolonged period of time without the risk of undesirable side effects such as ochronosis. Tolerance for the product was excellent as well, both for daytime and night-time formulations, and neither irritation reactions nor allergic reactions were present during the period of use. Conclusions: The combined use of active substances is similar and comparable to hydroquinone in a 60 day period. The foundation can be laid for future studies to approach a new investigation with a larger number of patients, in which the use of hydroquinone can be established in comparison with this new treatment, so as to allow a statistically significant relationship to be established. Additionally, by studying a larger number of participants, it would allow this new product to be set up as an effective alternative treatment for melasma. Fri, 01 Jan 2016 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/2933 2016-01-01T00:00:00Z