The Moldovan Medical Journal, Vol. 60, No 2, April 2017

The Moldovan Medical Journal. April 2017, Vol. 60, No 2

Sun, 01 Jan 2017 00:00:00 GMT

The Moldovan Medical Journal. April 2017, Vol. 60, No 2 The journal was founded in 1958 on the initiative of Nicolae Testemitsanu, an outstanding expert in orthopedics, social medicine, and public health. Now the publisher of the journal is the Scientific Medical Association of Moldova and the journal has become the scientific peer-reviewed periodical Edition designed for specialists in the areas of medicine, dentistry, pharmacy, social medicine, and public health. From its debut the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The aim of the Moldovan Medical Journal is to provide the international community with the results of scientific researches performed in the medical institutions of Moldova and inform Moldovan medical society about the advanced achievements of medicine abroad. The Editorial Board warmly welcomes both the readers of and the authors of the journal, all those who are enthusiastic about searching for new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution to the science of medicine will find our journal helpful and encouraging. Fondatori: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu”

Monograph “Pituitary adenomas. Morphopathology and molecular profile”, the author: Eugen Melnic

Sun, 01 Jan 2017 00:00:00 GMT

Monograph “Pituitary adenomas. Morphopathology and molecular profile”, the author: Eugen Melnic Vataman, Vladimir Department of Morphopathology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova

Cranial deformities as a risk factor in the harmonious development of oral and maxillofacial region

Sun, 01 Jan 2017 00:00:00 GMT

Cranial deformities as a risk factor in the harmonious development of oral and maxillofacial region Railean, Silvia Background: There is no information about cranio-facial asymmetry among school children and the influence of this pathology on the quality of life. Material and methods: The study presents a descriptive analysis of 3923 children ages 7 to 18 years. In this scientific work were involved three types of schools: 421 children from schools with severe neurological disorders; 2157 children from auxiliary schools with special educational needs; and 1345 children from pre-university schools. Buccal examination included the dento-maxillary analysis in three planes (sagittal, vertical, and horizontal) and cranial anatomical shape was examined for all children. Results: In total 3923 children were examined, of which 632 (16%) were determined with cranial asymmetry. Among 2157 children from auxiliary schools for children with special educational needs 18% were detected with cranial deformities. In schools for children with neurological disabilities cranial asymmetries were detected in 44.18%, and in pre-unuversity schools 4.76 % were found with cranial deformities. A high incidence (twice more) of dental alveolar anomalies were found in children with cranial deformities, compared to those without deformities in the sagittal plane, 15.5% of children with cranial deformities were found with dento-alveolars anomalies and 7.84% in children without cranial deformation was (P<0.001). Similar results were found in the determination of occlusion anomalies in the horizontal and vertical planes. Conclusions: The high incidence of cranial deformities was found among handicapped children and children from schools with special educational needs. A few children with cranial deformities were found among children from pre-university schools. It was proved that a high risk of dento-alveolar anomalies have children with cranial deformities. Department of maxillofacial surgery, pedodontics and orthodontics, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, of the Republic of Moldova

Radiofrequency ablation – new insights into the modern treatment of atrial flutter and fibrillation

Sun, 01 Jan 2017 00:00:00 GMT

Radiofrequency ablation – new insights into the modern treatment of atrial flutter and fibrillation Grib, Liviu; Cenusa, Octavian; Varvariuc, Viorica; Abraș, Marcel; Grib, Andrei; Grajdieru, Romeo Background: Atrial fibrillation (AF) is associated with a 5-fold increase in the risk of stroke and a 3-fold increase in the incidence of heart failure. The increase in AF prevalence can be attributed both to better detection of silent AF, alongside increasing age and conditions predisposing to AF. Nonpharmacological measures aimed at «healing» AF were initially tested in open surgery. Searching for an approach with a greater chance of success led to the development of radiofrequency ablation (RFA). Only recently RFA technique began to be used extensively in people with AF, not being tested in large randomized studies, with establishment of remote results. Conclusions: Catheter ablation is used successfully in patients suffering from symptomatic paroxysmal atrial fibrillation, as an alternative to drug therapy. Performed correctly by a trained and experienced electrophysiolologist, RFA allows us to get remarkable results, being possible suspension of treatment with antiarrhythmic drugs and to avoid its so well known side’s effects. RFA with catheter is superior to antiarrhythmic drug therapy in preventing recurrence in both persistent AF and in the paroxysmal AF. The success rate of RFA in experienced centers for paroxysmal AF exceeds 70% a year. RFA reintervention is necessary in the approximately 9-20% of patients with more modest results. The frequency of major complications related to RFA is less than 5%. The restored sinus rhythm with RFA in patients with heart failure may be associated with significant improvement in left ventricular ejection fraction. Department of Internal Medicine, Medical clinic No 3, Discipline of Cardiology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova