http://repository.usmf.md:80/xmlui/handle/20.500.12710/17896 Sat, 13 Jun 2026 16:29:17 GMT 2026-06-13T16:29:17Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/16263 The Moldovan Medical Journal. October 2017, Vol. 60, No 3 The journal was founded in 1958 on the initiative of Nicolae Testemitsanu, an outstanding expert in orthopedics, social medicine, and public health. Now the publisher of the journal is the Scientific Medical Association of Moldova and the journal has become the scientific peer-reviewed periodical Edition designed for specialists in the areas of medicine, dentistry, pharmacy, social medicine, and public health. From its debut the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The aim of the Moldovan Medical Journal is to provide the international community with the results of scientific researches performed in the medical institutions of Moldova and inform Moldovan medical society about the advanced achievements of medicine abroad. The Editorial Board warmly welcomes both the readers of and the authors of the journal, all those who are enthusiastic about searching for new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution to the science of medicine will find our journal helpful and encouraging. Fondatori: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu” Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/16263 2017-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/2708 Clinical presentation, risk factors and outcomes of tuberculosis in military recruits Lesnic, Evelina; Kulcitkaia, Stela; Niguleanu, Adriana Background: Tuberculosis represents the major threat for the health protection in the military forces. The aim of this retrospective and descriptive study was the evaluation of risk factors, clinical presentation and treatment outcomes of tuberculosis in military recruits. Material and methods: 51 military recruits with tuberculosis diagnosed during 01.01.2010-31.12.2015 in Chisinau military quarters and managed in the Hospital of Pneumophtysiology were assessed. Results: Most of military recruits aged 18-22, were residents of the rural localities, graduated incomplete general school or lyceum and were economically vulnerable. One half of the group consisted of active smokers and every tenth patient abused alcohol. Every fourth patient had tuberculosis in childhood and every tenth had family contact with a tuberculosis-affected person. Disease’s insidious onset was established in one half of the group and the acute onset in every fourth patient. Every tenth patient was diagnosed with tuberculosis within the first 6 months after the enrollment. Only one half of the groups were symptomatic patients, who complained of cough, asthenia and loss of weight. Pulmonary infiltrative tuberculosis predominated among recruits. Extensive infiltrates and involvement of both lungs were identified in a lower proportion. The high rate of successful treatment outcome was endangered by the high rate of lost to follow-up patients, demonstrating poor evaluation and follow-up after the discharging from the hospital. Conclusions: The epidemiological studies among military recruits are limited. The high rate of young, economically vulnerable men with risk factors demonstrates their priority for active screening. Treatment outcomes must be improved by the implementation of the adequate follow-up after hospital discharging. Department of Pneumophthisiology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/2708 2017-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/2710 Overview of evolution of premature mortality from major cardiovascular diseases in the Republic of Moldova, 2003-2015 Raevschi, Elena Background: Cardiovascular disease is the leading cause of mortality at the global and national level. Ischeamic heart diseases, cerebrovascular diseases and hypertensive heart disease together identify a highest proportional mortality that defines them as major contribution cardiovascular diseases worldwide. Premature mortality analyzing compared to traditional moves target from classical focus on the occurrence of deaths to focus on the losses caused by these deaths. The purpose of the study is to assess the premature mortality evolution from major cardiovascular diseases among adults in the Republic of Moldova for the period of 2003-2015. Material and methods: the research is a descriptive population study over the time of 13 years. The premature mortality phenomenon was counted in the years of potential life lost (YPLL). Age-adjusted rates were calculated using the direct method of standardization applying WHO World Standard Population Distribution (%) based on world average population between 2000-2025. Results: Overall period from 2003 to 2015, premature mortality rate from ischeamic heart diseases (+10.7%) and hypertensive heart disease (+41%) have registered increasing trends versus premature mortality rate from cerebrovascular diseases with decreasing trend (-23.9%). All together determined the decreasing trend (-2.4%) of major cardiovascular diseases premature mortality rate. When analyzing percentage changes of premature mortality increasing trends by age, the study findings identified the higher percentage changes in younger groups for ischeamic heart diseases premature deaths than hypertensive heart disease. Conclusions: Despite the general decreasing trend of major cardiovascular diseases premature mortality rate, ischemic heart diseases compared to cerebrovascular and hypertensive heart disease identify the most pronounced trends of the deaths event rejuvenation in the Republic of Moldova for the period 2003-2015. Nicolae Testemitsanu Department of Social Medicine and Health Management, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/2710 2017-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/2709 Metabolism and physiological effects of carbon dioxide. Implications in anaesthetic management Rusu, Victoria Background: Carbon dioxide is a normal by-product of aerobic metabolism that maintains the equilibrium of respiratory act, being eliminated from the lungs. Despite of an increasing number of researches concerning carbon dioxide metabolism and its effects on human homeostasis, there are still discussions about carbon dioxide metabolism, physiology and its implication in anaesthetic management, ICU, critically ill patient. The use of mild to moderate hypercapnia during general anaesthesia and in mechanically ventilated patients is growing, based on scientifical researches of last years. Material and methods: There has been scientifically evaluated data from PubMed, 2002-2017. Key words used in search are: “carbon dioxide”, “ventilation”, “metabolism”, “gas change”. There were selected articles, taking in consideration their title, and chosen abstracts. The article contains a qualitative analysis and synthesis of the recommendation, concerning anaesthetic management and metabolism of carbon dioxide. Conclusions: Carbon dioxide metabolism and its anaesthetic management, represents a challenge that will be actual for many years in future. The amount of controversial studies about effects of carbon dioxide on patients under general anaesthesia or mechanical ventilation, determined us to perform a review of literature, and evaluate it. There are known facts about carbon dioxide metabolism, such as normal values, how it is produced in human body, how it is evacuated, effects on cardiovascular, nervous systems, and still there are many controversial studies on that topic, that determine to study it more and find new research results. Valeriu Ghereg Department of Anesthesiology and Reanimatology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/2709 2017-01-01T00:00:00Z