http://repository.usmf.md:80/xmlui/handle/20.500.12710/20496 Sun, 12 Apr 2026 14:22:45 GMT 2026-04-12T14:22:45Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/20715 Moldavian Journal of Pediatric Surgery. 2017, No. 1 Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/20715 2017-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/20714 Reconstructive operations of serious scoliotic deformation at children Shavga, N.N.; Shavga, N.Gh. In Clinic of Vertebrology, Orthopedics and Traumotology of the “N.Georgiu” Scientifically-Practical Center of Children’s Surgery 58 children with scoliosis (>70°) of different etiology, have been pre- and postoperatively examined with a follow-up of 1 to 5 years. The comparative analysis of the quality of the life of patients with severe spine deformations (according to a questionnaire „EQ-5D”), before and after surgical intervention, has shown that quality of the life of patients in postoperative period essentially improved, in comparison with the preoperative period, from 12,7±0,3 points to 7,02 ± 0,1. The distant results of surgical treatment were: good – 39 (68,4%), satisfactory – 12 (21,1%), unsatisfactory – 7 (12,3%). The differential election of treatment option in spine deformation management depends on the age of patient, extent of deformation, spine mobility and neurological impairment. Application of high technologies allows achieving good results in these patients. Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/20714 2017-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/20690 Particularities of tissue regeneration of decellularized bovine pericardium xenografts used in the reconstruction of the anterior abdominal wall defects in the experimental model Negru, I. The purpose of this study was to evaluate the regeneration potential of decellularized bovine pericardium grafts used as an option to close the abdominal wall defects in the experimental model. The study group consisted of pigs subjected to reconstructive surgery of congenital abdominal wall defects (group 1 - 3 animals) (fig. 1) and total defect of the abdominal wall created surgically (involving all layers, including the peritoneum) with decellularized bovine pericardium (group 2 - 3 animals). Animals were sacrificed and investigated 30 days (3 animals) and 90 days after surgery (3 animals). he results of this experimental study have allowed us to conclude the following: - The acellular bovine pericardium graft is characterized by strength and durability, favorable for the reconstruction of major abdominal wall defects. - In the regenerative-reparative processes of the acellular bovine pericardium grafts used in the reconstruction of the abdominal wall defects together with fibrogenesis processes, there are also processes of metaplasia with differentiation in chondroblasts which induce the neoformation of cartilage foci in the biological implant, which, then functions as an enchondral ossification factor with the formation of trabecular osteogenesis and ossification foci. - The results obtained imply the need for further studies to clarify the role of these changes in the development of potential follow-up postoperative complications. Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/20690 2017-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/20669 In vivo evaluation of xenogeneic acellular bovine fascia grafts in the reconstruction of abdominal wall defects in swine experimental model Negru, I. In this study autor purpose to evaluate the feasibility of using bovine fascia in the experimental substitution of the fascial plan for the reconstruction of major anterior abdominal wall defects in the experimental model. Plastic reconstruction of the surgically induced abdominal wall defect using decellularized bovine fascia grafts was performed on 5-week-old Landrace pigs (3 animals) in which the abdominal wall defect of 10x5.0 cm was surgically induced with the involvement of all layers, including the peritoneum. The animals were subsequently euthanized 90 days after the intervention. For decellularization, sterile 0.5% SDS solution (HiMedia) was used in volume required to obtain acellular tissues. The solution was changed every 24 hours for 72 hours. The preventive results of the histopathological examination allowed the author to conclude that the use of decellularized bovine fascia grafts in the experimental model is characterized by the dominance of active regenerative processes with tissue remodeling and host cell invasion, the xenogeneic implant tissues being subjected to gradual degradation and substituted with the neoformed host connective tissue, the rationale of the usefulness of this biological material requiring additional comparative and clinical immunological studies. The results of this experimental study allow us to conclude the following that the usage of bovine fascia acellular grafts as an alternative xenogeneic biological implant in reconstructive surgery of abdominal wall defects, this option requiring additional comparative and clinical immunological studies. Sun, 01 Jan 2017 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/20669 2017-01-01T00:00:00Z