http://repository.usmf.md:80/xmlui/handle/20.500.12710/531 Moldovan Journal of Health Sciences Tue, 07 Apr 2026 01:08:20 GMT 2026-04-07T01:08:20Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/33047 The role of odontogenic infection in the onset and evolution of focal disease Ciobanu, Sergiu; Marcu, Diana; Roman, Ion; Musteață, Olesea Thu, 01 Jan 2026 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/33047 2026-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/32479 Refractive lens exchange in a patient with high myopia and myopic astigmatism: a clinical case report Porada, Serghei; Tanurcova, Iulia; Paduca, Ala Introduction. Refractive lens exchange is increasingly utilized for visual rehabilitation in patients with high myopia unsuitable for corneal refractive procedures. While effective, refractive lens exchange with intraocular lens implantation significantly improves visual acuity in young patients with high myopia and astigmatism, while maintaining a low risk of postoperative retinal complications, provided that thorough preoperative vitreoretinal assessment is conducted. However, it carries potential risks, notably retinal complications. Case presentation. We present a case involving a 45-year-old female with high axial myopia and myopic astigmatism who underwent bilateral refractive lens exchange with the implantation of monofocal intraocular lenses. Comprehensive preoperative assessments included optical biometry, tonometry, fundus examination, and visual acuity measurements. Postoperative recovery was uneventful in the right eye. However, the patient developed a retinal detachment in the left eye approximately one year post-surgery. This complication was successfully managed with pars plana vitrectomy, endolaser photocoagulation, and silicone oil tamponade, resulting in an improvement of visual acuity to 0.3. Conclusions. Refractive lens exchange can be an effective intervention for patients with high axial myopia but carries a risk of retinal detachment. Thorough preoperative evaluation, meticulous surgical technique, and patient counseling are essential. Prompt detection and management of complications like retinal detachment are crucial for preserving visual outcomes. Wed, 01 Jan 2025 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/32479 2025-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/32478 Digital planning in orthodontics. Applicability of the Kau, Pan, Gallerano index in contemporary orthodontics Trifan, Valentina; Bolgari, Ana; Baiceva, Iana; Trifan, Daniela; Zumbreanu, Irina Introduction. Digital planning in modern orthodontics is crucial in contemporary era, as it allows dentists to expand the limits of patients’ diagnosis and clinical treatment. Using tools such as 3D scanners, cone beam computed tomography with various software gives clinicians the opportunity to achieve more precise diagnoses and accurate predictions of treatments. In this way, digital imaging offers a precise localization of impacted canines which allows for the integration and applications of the Kau, Pan, Gallerano index. Material and methods. To assess the applicability of the Kau, Pan, Gallerano index and digital planning in orthodontics, this review evaluates key studies that explore various aspects of the topic. Scientific databases such as Cochrane Library, Medline, Scopus, Medicus, NCBI, PubMed, and Google Scholar were used to find the necessary articles. Research methods like analysis, synthesis, systematization and description were applied. Results. After analyzing the available data, this review presents the benefits and opportunities of digital orthodontics. The findings demonstrate that the Kau, Pan, Gallerano index offers high diagnostic accuracy by effectively categorizing various types of impactions. Moreover, the analysis reveals a strong correlation between the Kau, Pan, Gallerano index scores and successful treatment outcomes, showing that the index with digital technologies improves diagnostic accuracy and treatment planning. Conclusions. The reviewed literature collectively indicates that this index is a valuable tool in contemporary digital orthodontics. Its interdisciplinary connection with digital planning which provides strong predictive value, and its comprehensive assessment approach make it an important component in modern orthodontic practice. Future research should continue to explore the advantages and disadvantages of modern technologies used in orthodontic diagnosis and treatment planning, thus validating their efficiency and their applicability across diverse complex orthodontic cases. Wed, 01 Jan 2025 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/32478 2025-01-01T00:00:00Z http://repository.usmf.md:80/xmlui/handle/20.500.12710/32477 β-adrenergic agonists and β-antagonists in sport performance: a narrative synthesis of pharmacological effects and anti-doping implications Chiriac, Tatiana; Pogonea, Ina; Timercan, Tatiana; Jucov, Artiom; Stratulat, Silvia; Tăbîrță, Alisa; Chihai, Victoria Introduction. In the context of increasingly intense athletic competition, athletes are motivated to enhance their performance through various methods, including the use of pharmacological substances that act on the adrenergic system. Among these, β2-adrenergic agonists are employed for their metabolic effects and their role in increasing endurance, whereas β-adrenergic antagonists are used in precision sports to reduce tremor and control anxiety. Both classes of substances present potential benefits as well as health risks, and are subject to strict regulations in high-performance sports. Material and methods. A theoretical study was conducted based on the analysis of specialized scientific literature, aiming to evaluate the impact of β2-adrenergic agonists and β-adrenergic antagonists on athletic performance. Additionally, the current regulations of the World Anti-Doping Agency (WADA) were analyzed. Results. β2-adrenergic agonists may contribute to the stimulation of muscle protein synthesis, enhancement of energy metabolism, and delay in the onset of fatigue. However, their use is associated with significant cardiovascular and metabolic side effects. β-adrenergic antagonists are effective in reducing tremor and sympathetic activation in precision sports but may decrease overall exercise capacity and induce bradycardia or chronic fatigue. Improper use of these substances can lead to severe sanctions in the context of athletic competitions. Conclusions. Although β2-adrenergic agonists and β-adrenergic antagonists may offer certain advantages depending on the specific nature of the sport, their use must be strictly medically regulated and comply with anti-doping standards. Careful evaluation of the risk-benefit ratio is essential for safeguarding athletes’ health and preserving the integrity of competition. Wed, 01 Jan 2025 00:00:00 GMT http://repository.usmf.md:80/xmlui/handle/20.500.12710/32477 2025-01-01T00:00:00Z