ARTICOLE ȘTIINȚIFICE

Romanian translation and validation of vascular quality of life questionnaire “VascuQOL-6” in patients with lower extremity arterial disease

Sun, 01 Jan 2023 00:00:00 GMT

Romanian translation and validation of vascular quality of life questionnaire “VascuQOL-6” in patients with lower extremity arterial disease Predenciuc, Alexandru; Culiuc, Vasile; Nordanstig, Joakim; Morgan, Mark B.F. Background: Patient reported outcomes are valuable components in the assessment of results of treatment for peripheral arterial disease (PAD). The aim of the study was totranslate the six item Vascular Quality of Life Questionnaire (VascuQoL-6) survey intoRomanian, and to validate the psychometric performance of the questionnaire in a representative cohort of patients with lower extremity arterial disease. Material and Methods: Translation of the VascuQoL-6 questionnaire was performed following accepted methodology. The overall validation cohort included 100 patients withPAD (86% with chronic limb-threatening ischemia) undergoing lower limb revascularization.In 20 patients with stable PAD two questionnaires were offered preoperatively with a median interval of 15 days. Another 22 patients were re-tested after revascularization at amedian interval of 30 days. Results: The median time required for completion of the VascuQoL-6 survey was 2 (IQR 2-3) minutes. The translated version demonstrated high internal consistency (Cronbach’s alpha– 0.81) and there was no difference in the preoperative median VascuQoL-6 scoring duringthe test re-test assessment. Area under the ROC curve for ability to discriminate intermittentclaudication from chronic limb-threatening ischemia was 0.897. The median VascuQoL-6score increased from 10 (IQR 8-12) points preoperatively to 18.5 (IQR 14.7-20) points post-operatively (p < 0.0001) with a standardized response mean of 2.94. Conclusion: The Romanian version of the VascuQoL-6 survey demonstrated good reliability,validity and responsiveness and can thus be recommended for use in patients with lowerlimb PAD.

Controverse privind riscul emboligen şi managementul optim al trombozei flotante a venelor profunde

Wed, 01 Jan 2014 00:00:00 GMT

Controverse privind riscul emboligen şi managementul optim al trombozei flotante a venelor profunde Guţu, Evghenie; Culiuc, Vasile; Sochircă, Marcel; Casian, Dumitru; Donţu, Igor Background. It is suggested that free-floating form of deep venous thrombosis, especially that with proximal location, is associated with a higher rate of pulmonary embolism. The aim of current study was to estimate the risk of symptomatic embolism occurrence in pts with free-floating thrombus and to perform comparative analysis of early results of conservative versus surgical treatment in these cases. Methods. In a prospective investigation were included 69 pts (mean age: 56,82 years) with free-floating thrombi, defined by duplex ultrasound as presence of unattached to vein wall thrombotic apex with clearly visualized oscillatory movement. Fifty-two pts were treated surgically by means of venous plication (n=38; 73,07%) or ligation (n=14; 26,92%) asociated in some cases with partial thrombectomy (n=11), remaining 17 pts receiving anticoagulation treatment (adjusted doses of low molecular weight heparins with subsequent conversion to vitamin K antagonists). Results. Frecvency of simptomatic pulmonary embolism at admission or during hospitalization was 11,59%, while rate of diagnosed episodes of embolization rise to 18,84. The incidence of symptomatic pulmonary embolism in conservative group was 23,52% vs. 0% - recorded postoperatively (p<0,05; t-test), but rate of embolism-related death was 11,76% vs. 0%, respectively (p-NS; t-test). Conclusions. It is necessary to clarified and unified diagnostic criteria of free-floating thrombus. Until then clinical significance of free-floating thrombi cannot be objectively evaluated. Efficacy of both surgical and conservative treatment for prevention of massive pulmonary embolism in pts with free-floating thrombosis needs to be established on a larger clinical cases group. Catedra Chirurgie Generală Semiologie, IP Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu” (Moldova) Copyright © 2019 – The Balkan Medical Union

Recurenţa maladiei varicoase: incidenţă şi clasificare (Revista literaturii)

Wed, 01 Jan 2014 00:00:00 GMT

Recurenţa maladiei varicoase: incidenţă şi clasificare (Revista literaturii) Maloghin, Vasile Boala varicoasă a membrelor inferioare are o creştere a incidenţii la nivel mondial în ultimii ani. În pofida faptului că au apărut noi metode de tratament sau au fost modernizate cele vechi, rata recidivei postoperatorii a maladiei varicoase rămâne înaltă şi nu are tendinţă spre scădere. Dacă în diagnosticul clinic şi imagistic au fost stabiliţi piloni de consens asupra conduitei operatorii a bolii varicoase, atunci datele actuale din literatură suferă nişte lacune a uniformităţii, atunci când se propune de a defini recidiva bolii varicoase, timpul apariţiei şi metodele folosite pre- şi post operatorii de a scădea rata acesteia. Varicose veins of the lower limbs have an increased incidence worldwide in recent years. Despite the fact that there were new methods of treatment or were upgraded old ones, postoperative recurrence rate of varicose veins remains high and has not a tendency to decrease. If in the clinical and imaging diagnosis have been established points of consensus on the operative management of varicose veins, then the current data in the literature suffer from some uniformity gaps, when it is proposed to define recurrence of varicose veins, time of appearance and the methods used pre- and postoperative to reduce its rate. Частота варикозного расширения вен нижних конечностей в последнее время растет во всем мире. Несмотря на появление новых методов лечения и улучшение старых, частота рецидива варикозной болезни остается высокой и не имеет тенденции к снижению. Если в клиническом и диагностическом плане был достигнут консенсус по методике операции при варикозном расширении вен, то понятие рецидива варикозной болезни, сроки появления и методы снижения его частоты остаются спорными по данным современной медицинской литературы. Catedra Chirurgie Generală şi Semiologie Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Moldova

Хирургические и малоинвазивные вмешательства на перфорантных венах голени при варикозной болезни (обзор литературы)

Fri, 01 Jan 2016 00:00:00 GMT

Хирургические и малоинвазивные вмешательства на перфорантных венах голени при варикозной болезни (обзор литературы) Касьян, Д.А. Резюме. Вмешательства на несостоятельных перфорантных венах голени у пациентов с хронической венозной недостаточностью относятся к спорным вопросам современной флебологии. Выполнен обзор литературы, отражающей эволюцию хирургических подходов в лечении патологического рефлюкса крови по перфорантным венам, а также критический анализ показаний, результатов, преимуществ и ограничений открытых хирургических, эндоскопических и эндовенозных техник. Резюме. Втручання на неспроможних перфорантних венах гомілки у пацієнтів з хронічною венозною недостатністю відносяться до спірних питань сучасної флебології. Виконано огляд літератури, що відображає еволюцію хірургічних підходів у лікуванні патологічного рефлюксу крові по перфорантних венах, а також критичний аналіз показань, результатів, переваг та обмежень відкритих хірургічних, ендоскопічних і ендовенозних технік. Abstract. Interventions on incompetent perforating veins of the leg among patients with chronic venous insufficiency represent a controversial issue in modern phelbology. The evolution of surgical options, applied for treatment of pathological reflux through perforating veins, was reviewed with critical analysis of indications, results, advantages and limitations of open surgical, endoscopic and endovenous techniques. Государственный университет медицины и фармации им. Н.А. Тестемицану, Кишинев, Республика Молдова