Цитология структурно-функциональных зон лимфоузлов разных анатомо-топографических групп

Abstract

Abstract Background: Morphological evaluation of functional changes of the lymph nodes is an integral part of fundamental research. The study of the peculiarities of the cellular composition in different topography groups of lymph nodes there is interest in understanding General regularities of the structure and function of lymph nodes. Material and methods: We studied the cellular composition of lymph nodes in different locations in white rats aged 3-5 months in the experiment. The object of the study was inguinal, mesenteric, tracheobronchial lymph nodes. Histological sections were stained with hematoxylin and eosin, azure and eosin. We counted the number of cells on a standard square in morphometrics. Statistical method was determined arithmetic average, root mean square error and the significance of differences. Results: It is shown that the structural and functional areas of the lymph node there is a difference in the number of basic lymphoid cells that determines the characteristics of the cellular composition of lymph nodes in different locations. The numerical density of meddle lymphocytes differ in lymphoid nodule, increasing successively in a row: inguinal – mesenteric – tracheobronchial lymph nodes; the numerical density of lymphoblasts differs in paracortex, decreasing successively in a row: inguinal – mesenteric – tracheobronchial lymph nodes; the numerical density of lymphoblasts, macrophages differs in medullary cords, decreasing in a row: inguinal – mesenteric – tracheobronchial lymph nodes. We observed the lowest number of small lymphocytes in the medullary sinus of the inguinal lymph node and marked the highest number of macrophages in the medullary sinus of the tracheobronchial lymph node. We observed the lowest number of reticular cells, macrophages in paracortex tracheobronchial lymph node, and we have noted the greatest number of plasmocytes in medullary cords of the mesenteric lymph node. Conclusions: The immunomorphological status of lymph nodes is in direct proportion to the lymphatic region and the functional state of the drained organ. The difference of cellular composition in the structural and functional areas varies in a row: inguinal – mesenteric – tracheobronchial lymph nodes, which defines the different degrees of immunoreactivity.