Abstract:
Summary
We evaluated the prognostic significance of a second transurethral resection in patients with
moderately differentiated Ta-1 bladder cancer. The information was gathered from MEDLINE,
current urology journals, abstracts from recent urological meetings and personal experience. A total
of 31 patients with primary T1 bladder cancer were evaluated. A second transurethral resection was
performed in 8 patients in case of moderately differentiated Ta-1 bladder tumor or concomitant
carcinoma in situ in the first resection. Of the 31 patients who underwent repeat resection 8 (26%)
had no residual tumors. Residual tumor after the first transurethral resection presents a commin
finding in bladder cancer patients. The second transurethral resection offers a possibility to preserve
the bladder. Furthermore, residual disease can be detected and removed. In case of upstaging to
muscle infiltrating tumor, cystectomy is the next therapeutic step.