Characteristics of clinical manifestations of gout in the elderly people

Abstract

Introduction. Gout in elderly patients is characterized a pronounced comorbid background [2,8-10], which causes difficulties in their management [9]. Objectives of the study. Analysis of the comorbid background for gout in different age groups. Identification of risk factors characteristics, the onset and evolution of gout in elderly people compared to middle-aged patients. Material and methods. To achieve the goal of the cross-sectional study, 237 patients with gout (average age for the men 60±8.0 years and for the women 63±9.0 years) were examined. Results. The patients were separated into two groups, depending on the age of onset of gout: the age of onset up to and including 59 years (group I, 146 people) and the age of onset after 60 years inclusive (group II, 91 people). The average age in group I was 58.1±11.7 years, in group II - 72.8±4.1 years (p<0,1). Conclusions. The average number of concomitant diseases is 2 times higher in the group of gout patients aged 60 years and older (4.0 [3.0; 5.0]) than in the group of patients with gout under the age of 59 years inclusive (2.0 [2.0;3.0], p <0,1), in patients with the onset of gout at the age of 59 years inclusive, the development of coronary artery disease, chronic heart failure and nephrolithiasis occurs significantly earlier than in patients with the onset of gout at the age of 60 years and older (48,4±6,9 years and 59,1±5,0 years; 53,6 ± 3,4 years and 65,6±9,0 years; 37,3±8,9 years and, respectively, 54,9±14,6 years, p<0,05 in all cases).