dc.contributor.author |
Vataman, Eleonora |
|
dc.contributor.author |
Ivanov, Victoria |
|
dc.contributor.author |
Abraş, Marcel |
|
dc.contributor.author |
David, Lilia |
|
dc.contributor.author |
Carauş, Alexandru |
|
dc.contributor.author |
Moscalu, Vitalie |
|
dc.contributor.author |
Sapojnic, Nadejda |
|
dc.contributor.author |
Diaconu, Nadejda |
|
dc.contributor.author |
Plugaru, Ana |
|
dc.contributor.author |
Cazacu, Janna |
|
dc.contributor.author |
Cobeţ, Valeriu |
|
dc.date.accessioned |
2024-12-19T08:04:43Z |
|
dc.date.available |
2024-12-19T08:04:43Z |
|
dc.date.issued |
2020 |
|
dc.identifier.citation |
VATAMAN, Eleonora, IVANOV, Victoria, ABRAŞ, Marcel, et al. COVID-19 și sistemul cardiovascular: concepte și viziuni actuale. In: Buletinul Academiei de Științe a Moldovei. Ştiinţe Medicale. 2019, vol. 65, no. 1, pp. 9-47. ISSN 1857-0011. |
en_US |
dc.identifier.issn |
1857-0011 |
|
dc.identifier.uri |
https://bulmed.md/bulmed/article/view/3165/3165 |
|
dc.identifier.uri |
http://repository.usmf.md/handle/20.500.12710/29034 |
|
dc.description.abstract |
Summary. COVID-19 and cardiovascular system: concepts and current visions Background. SARS-CoV-2 action triggers and exacerbates cardiovascular disorders that underlines an intelligible necessity for a large researching of the inherent mechanisms and peculiarities needed for a diagnosis and depiction of the pathogenic therapy targets. Aim. This synthesis article embraced the known and plausible entities regarding the interface of COVID-19 and cardiovascular disturbances: from pathophysiology up to therapeutic approaches.Results. The main pathophysiological link between SARS-CoV-2 and circulatory homeostasis is based on Ang 1-7 deficiency, cytokinic storm and viremia basically leading to injury of cells having receptors for virus intracellular enter-ing: ACE2 and CD209. Diagnostical tests are provided thereby of real time PCR and serological settings for immuno-globulins detection. There were noted particularities of the management of patients with STEMI and NSTEMI. Likewise, the evolution and treatment of the main cardiac arrhythmias in COVID-19 are tackled. Arterial hypertension, acute and chronic heart failure are also analyzed in patients infected by SARS-CoV-2. A special glance is thrown to problems of hemostasis in COVID-19 concerning thrombosis, fibrinolytic system disorders and treatment traits. The guidance concept of triage of the patients eligible to cardiac surgery in COVID-19 is emphasized also. Finally, this article comprises the specific elements of the pharmacological treatment of patients with cardiovascular disorders in COVID-19. |
en_US |
dc.language.iso |
ro |
en_US |
dc.publisher |
Academia de Stiinte a Moldovei |
en_US |
dc.subject |
SARS-CoV-2 |
en_US |
dc.subject |
circulatory homeostasis |
en_US |
dc.subject |
Ang 1-7 |
en_US |
dc.subject |
ACE2 |
en_US |
dc.subject |
cardiovascular disorders |
en_US |
dc.title |
COVID-19 și sistemul cardiovascular: concepte și viziuni actuale |
en_US |
dc.title.alternative |
COVID-19 and cardiovascular system: concepts and current visions |
en_US |
dc.type |
Article |
en_US |