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Comparative cellular local response in abdominal defect plastic surgery with bovine pericardium and bovine fascia preserved in formaldehyde in experimental rabbits

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dc.contributor.author Gudumac, Eva
dc.contributor.author Babuci, Stanislav
dc.contributor.author Tica, C.
dc.contributor.author Petrovici, Virgil
dc.contributor.author Nacu, Viorel
dc.contributor.author Ionescu, C.
dc.contributor.author Negru, Ion
dc.date.accessioned 2019-06-26T04:42:10Z
dc.date.available 2019-06-26T04:42:10Z
dc.date.issued 2017
dc.identifier.citation Gudumac, E., Babuci, S., Tica, C. [et al.]. Comparative Cellular Local Response In Abdominal Defect Plastic Surgery With Bovine Pericardium And Bovine Fascia Preserved In Formaldehyde In Experimental Rabbits. In: ARS Medica Tomitana. 2017, Vol. 23, Issue 2, pp. 83-93.
dc.identifier.issn 1841-4036
dc.identifier.uri https://www.degruyter.com/downloadpdf/j/arsm.2017.23.issue-2/arsm-2017-0016/arsm-2017-0016.pdf
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/5455
dc.identifier.uri DOI: https://doi.org/10.1515/arsm-2017-0016
dc.description State University of Medicine and Pharmacy “Nicolae Testemițanu”, Chisinau, Republic of Moldova, University "Ovidius" of Constanta, Faculty of Medicine en_US
dc.description.abstract ABSTRACT In the present paper, we refer to a method of primary closure of congenital defects of the anterior abdominal wall with tensionless viscero-abdominal disproportion. The study group included 10 animals subjected to surgery of the abdominal wall defect closure with bovine pericardium graft preserved in 0.5% formaldehyde, and 5 rabbits of the same breed and weight, in which bovine fascia graft was used as implant, being preserved in 0.5% formaldehyde. The abdominal anterior wall defect was made surgically by excision of the musculo-fascial structures and peritoneum. Bovine pericardium graft and bovine fascia graft were placed and fixed posteriorly to rectus abdominals muscles, having direct contact with the intra-abdominal contents and protected by suturing skin and subcutaneous layer. The purpose of the study was to perform a comparative postoperative evaluation of local macroscopic and microscopic changes that develop after reconstruction of the major abdominal wall defects experimentally induced in rabbits, using bovine pericardium and bovine fascia grafts preserved in 0.5% formaldehyde. In cases of major fascial defects of the anterior abdominal wall, bovine pericardium graft has acceptable strength and biocompatibility, having stabilizing properties of the abdominal wall due to the development of the connective tissue layer located between the implant and the subcutaneous layer. Bovine fascia grafts preserved in formaldehyde have an insignificant irritating and inflammatory action on the intestinal loops compared with bovine pericardium, and do not induce the development of a significant abdominal adhesion process, this allowing their use in the abdominal fascial defects closure with placement in direct contact with the abdominal contents. en_US
dc.language.iso en en_US
dc.publisher ARS Medica Tomitana en_US
dc.subject Abdominal Defect en_US
dc.subject Bovine Pericardiu en_US
dc.subject Bovine Fascia en_US
dc.subject.mesh Surgery, Plastic en_US
dc.subject.mesh Abdomen en_US
dc.subject.mesh Cattle en_US
dc.subject.mesh Pericardium en_US
dc.subject.mesh Fascia en_US
dc.subject.mesh Formaldehyde en_US
dc.title Comparative cellular local response in abdominal defect plastic surgery with bovine pericardium and bovine fascia preserved in formaldehyde in experimental rabbits en_US
dc.type Article en_US


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