IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Applicability of the CLDQ in the monitoring of patients with delta viral liver cirrhosis 
    Cebanu, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The clinical burden of delta viral cirrhosis is significant in terms of health, quality of life, and economic impact on patients and society. The Chronic Liver Disease Questionnaire (CLDQ) is an instrument ...
  • Chronic obstructive pulmonary disease and depression 
    Avadănii, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease encompasses various complications and comorbidities such as respiratory failure, cardiovascular disease, the development of lung cancer, osteoporosis, metabolic syndrome, ...
  • Diagnostic accuracy of Xpert Ultra for microbiological confirmation of pulmonary tuberculosis in patients with paucibacillary disease 
    Sîrbu, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Worldwide, up to one-third of pulmonary tuberculosis patients are missed for microbiological confirmation. Assessment of specimens obtained during bronchoscopy is one of the well-recognized methods that can ...
  • Laboratory markers in the diagnosis of hereditary gluten intolerance 
    Rotari, Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gluten intolerance (celiac disease) is a genetic autoimmune disease with a prevalence of approximately 1% of the population in which the consumption of gluten-containing foods causes damage to the small ...
  • Consequences of pulmonary hypertension and rightsided heart failure 
    Ursu, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pulmonary hypertension (PH) is common in several pathologies and maintains high levels of morbidity and mortality. In PH the main consequence is right heart failure, which leads to complex clinical syndrome ...
  • Vitamin D metabolism in hepatorenal syndrome 
    Harees, Noushad Juguma (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hepatorenal syndrome (HRS) is a consequence of liver cirrhosis, which is the final stage of chronic liver disease with irreversible damage and the existence of regenerating nodules. Renal function is disturbed ...
  • Acute viral infection as a trigger for DSNMG: a case report 
    Stafi, Vlada; Stavila, Iulia; Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Categorical evidence shows that patients with Acute Respiratory Viral Infections have a higher risk of concurrently developing autoimmune diseases, reflecting phenotypic heterogeneity in MG. The association ...
  • Transcutaneous auricular vagus nerve stimulation efficacy in drug resistant epilepsy treatment 
    Iurcu, Victoria; Olaru, Natalia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Transcutaneous auricular vagus stimulation (taVNS) modulates the locus coeruleus-norepinephrine (LC-NE) network through impulses delivered to the external ear via Aβ fibers using frequencies mostly between ...
  • Herpes zoster in patients with HIV/AIDS. Epidemiological, clinical and treatment features 
    Josan, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Herpes Zoster represents the phenotype, conditioned by the reactivation of the Varicella zoster virus from its latent phase. It manifests itself as viral ganglioneuritis with damage to the intervertebral ...
  • Telomere and telomerase function: safeguarding chromosomal ends and their implications in aging and cancer development 
    Batîr, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Telomeres, the protective caps at the ends of linear chromosomes, play a crucial role in maintaining genomic stability and integrity. As cells undergo repeated divisions, telomeres progressively shorten, ...
  • The clinical and immunological features of myasthenia gravis with anti-musk antibodies 
    Țîrdea, Alexei (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Myasthenia gravis is an autoimmune disorder of the neuromuscular junction, caused by autoantibodies synthesized against AChR, MuSK or LRP4. There is also a seronegative form, where antibodies are not detected. ...
  • Management of uterine fibroids and its complications during pregnancy 
    Goncearuc, Dumitrița (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Uterine fibroids are a very common finding in women of reproductive age. The major complication of myomas in pregnancy is recurrent pain, however, miscarriage is the main threat. The negative impact of fibroids ...
  • Auxiliary diagnostic methods for hydatidiform mole: a concise review 
    Latescu, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hydatidiform moles (HMs) are premalignant conditions within gestational trophoblastic disease (GTD). Early diagnosis is crucial due to the risk of malignant transformation, with neoplasia risks for complete ...
  • The consequences of сraniocerebral injuries caused by electric scooters 
    Andrianova, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The burgeoning popularity of electric scooters (ES) has been paralleled by a rise in associated craniocerebral injuries (CCIs). As these modern, portable vehicles gain widespread use in numerous developed ...
  • Epidemiological features of kaposi’s sarcoma with cutaneous involvement in the Oncological Institute of the Republic of Moldova over the years 2018-2023 
    Stascoveac Iadviga (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to GLOBOCAN 2020 database incidence is 34270 and mortality 15086 for both sexes and all ages. The most affected population is Africa, 73%, followed by European countries 8,8%. This disease becomes ...
  • Diagnosis of fetal growth restriction 
    Iuțis, Vlada; Catrinici, Rodica (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of intrauterine fetal growth restriction continues to rise with an increased risk of perinatal mortality and morbidity. Accurate recognition of Intrauterine Growth Restriction (IUGR) holds ...
  • Etiopathogenetic frontiers of trophoblastic neoplasms: a comprehensive review 
    Zingan, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Trophoblastic neoplasms, a heterogeneous group of gestational trophoblastic diseases, present intricate challenges in deciphering their etiological and pathogenetic underpinnings. While these rare gestational ...
  • Combined administration of docetaxel and apigenin inhibits breast cancer cell survival and migration 
    Nizamudeen, Fathima (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Breast cancer, an urgent global health issue, necessitates innovative therapeutic approaches. This study focuses on HER2-positive breast cancer characterized by overexpression of the HER2 gene. Apigenin, a ...
  • Etiology and diagnostic particulars of benign ovarian tumors 
    Ambrosiv, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the official data, the most widespread diseases of the reproductive system, at women of reproductive age, are ovarian tumors. The research results address the etiology and diagnosis of benign ...
  • Application of virtual reality (VR) in the planning and simulation of urgent neurosurgical interventions 
    Todica, Vladislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Emergency neurosurgery is required for acute cerebrovascular disorders, intracranial and spinal cord traumas, and pre-cerebral artery occlusion/stenosis. It requires immediate and accurate management. Virtual ...