IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Role of mineralocorticoid receptor pathway in the pathogenesis of diabetic retinopathy 
    Toncoglaz, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetic retinopathy (DR) represents a major cause of irreversible blindness among the working-age population. Aldosterone has an important role in the pathogenesis of DR, through vascular regulation, oxidative ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • Genetic variants of COMT gene expression and influence on pain perception 
    Crasevici, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Catechol-O-methyltransferase (COMT) is a pivotal enzyme responsible for deactivating biologically active catechols, including crucial neurotransmitters such as dopamine, norepinephrine, and adrenaline. These ...
  • Dietary habits of patients with ischemic heart disease 
    Abraș, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ischemic heart disease continues to be the leading cause of mortality, morbidit y and high hospitalization rates in both high-income and developing countries. According to data from the World Health Organization, ...
  • Personalized medicine and cardiovascular diseases 
    Sooltan, Abdool Rahim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There was a remarkable growth in scientific publication on personalized medicine within the past few years in the field of cardiovascular disease. In the era of personalized/precision medicine the combination ...
  • Simulation as an efficient training tool in obstetric emergencies 
    Coșpormac, Mihaela; Manic, Milena; Budianu, Cătălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Despite the era of high-tech medicine, high quality obstetric management requires a good collaboration between multidisciplinary professionals based on the improvement and acquisition of knowledge and practical ...
  • Methods of term labor induction for women with a previous caesarean section 
    Curlat, Vlad (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The term pertains to diverse methodologies employed for the initiation of parturition in gravid individuals who have previously had a cesarean section(c-sec) and have reached the full term gestational period. ...
  • Ovarian function in women of reproductive age after hysterectomy 
    Vataman, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. As a core reproductive organ, the ovary has two distinct functions, producing mature oocytes for fertilization and secreting sex hormones to sustain the normal activities of multiple organs. Aim of study. ...
  • Postpartum spontaneous hemoperitoneum and endometriosis – case report 
    Darii, Corina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Spontaneous hemoperitoneum in pregnancy (SHiP) is characterized by unprovoked intraperitoneal bleeding with an incidence rate of 1:10000 pregnancies. Endometriosis represents one of the main risk factors and ...
  • Prenatal diagnosis of fetal facial abnormalities in the first trimester of pregnancy 
    Ciobanu, Miruna-Olguța; Toma, Loredana-Maria; Covalciuc, Vladislava (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The fetal face is a complex anatomical structure due to its embryological elaborate development and represents an important key for fetal conditions and syndromes. Changes in the embryological development may ...
  • Management of uterine fibroids and its complications during pregnancy 
    Goncearuc, Dumitrița (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Uterine fibroids are a very common finding in women of reproductive age. The major complication of myomas in pregnancy is recurrent pain, however, miscarriage is the main threat. The negative impact of fibroids ...
  • The impact of obesity on pregnant women and fetus 
    Baxan, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity is a condition characterised by excess of body fat and low body mass (BMI ≥ 30). Statistics show that more than 50% of obese and overweight people in Europe are overweight, 26.5% of women of reproductive ...
  • Profile of women with pregnancy achieved through in vitro fertilization 
    Caliga, Gheorghe; Finciuc, Victor; Dondiuc, Iurie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pregnancy obtained through In Vitro Fertilization (IVF) has increased to 3-5% of all births worldwide. This is due to increasing infertility in couples as well as the development of fertilization techniques, ...
  • Perinatal outcomes in pregnancy with gestational diabetes 
    Vieru, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gestational diabetes mellitus (GDM) traditionally refers to abnormal glucose tolerance with onset or first recognition during pregnancy. The increasing obesity rate is leading to an increase in gestational ...
  • Epidemiological features of kaposi’s sarcoma with cutaneous involvement in the Oncological Institute of the Republic of Moldova over the years 2018-2023 
    Stascoveac Iadviga (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to GLOBOCAN 2020 database incidence is 34270 and mortality 15086 for both sexes and all ages. The most affected population is Africa, 73%, followed by European countries 8,8%. This disease becomes ...
  • Diagnosis of fetal growth restriction 
    Iuțis, Vlada; Catrinici, Rodica (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of intrauterine fetal growth restriction continues to rise with an increased risk of perinatal mortality and morbidity. Accurate recognition of Intrauterine Growth Restriction (IUGR) holds ...
  • Combined administration of docetaxel and apigenin inhibits breast cancer cell survival and migration 
    Nizamudeen, Fathima (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Breast cancer, an urgent global health issue, necessitates innovative therapeutic approaches. This study focuses on HER2-positive breast cancer characterized by overexpression of the HER2 gene. Apigenin, a ...
  • Etiology and diagnostic particulars of benign ovarian tumors 
    Ambrosiv, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the official data, the most widespread diseases of the reproductive system, at women of reproductive age, are ovarian tumors. The research results address the etiology and diagnosis of benign ...
  • Application of virtual reality (VR) in the planning and simulation of urgent neurosurgical interventions 
    Todica, Vladislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Emergency neurosurgery is required for acute cerebrovascular disorders, intracranial and spinal cord traumas, and pre-cerebral artery occlusion/stenosis. It requires immediate and accurate management. Virtual ...
  • Chorio-villous mesenchymal stromal dysplasia in the course of pregnancies 
    Grosu, Eugenia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stromal dysplasia is a developmental anomaly of the placenta that is characterized microscopically by dilated stem villi with a myxoid or hydropic appearance, cisterna lacunae, and lack of ...