The impact of statins on the metabolism of patients with cardiovascular disease

Abstract

Introduction. Statins are a class of lipid-lowering medications, also known as HMG-CoA reductase inhibitors. They are considered one of the most popular prescribed agents worldwide for treatment of hypercholesterolemia. Statins are effective drugs to reduce cardiovascular events and mortality secondary to dyslipidemia. Statin therapy is considered as the standard dyslipidemia therapy. Except lipid-lowering effect, it is known that statins have cholesterolindependent effects (pleiotropic effects).