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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/13777
Title: Evaluarea hemodinamicii portale la pacienţii cirotici trataţi chirurgical
Other Titles: Assessment of portal hemodinamics in patients with liver cirrhosis, treated surgically
Authors: Ţâmbală, C.
Dumbrava, Vt.
Cazacov, V.
Darii, E.
Ionaşcu, M.
Issue Date: 2015
Publisher: Asociaţia chirurgilor “Nicolae Anestiadi” din Republica Moldova
Citation: ŢÂMBALĂ, C., DUMBRAVA, Vt., CAZACOV, V., et al. Evaluarea hemodinamicii portale la pacienţii cirotici trataţi chirurgical = Assessment of portal hemodinamics in patients with liver cirrhosis, treated surgically. In: Arta Medica. 2015, nr. 3(56), pp. 185-186. ISSN 1810-1852.
Abstract: Introducere: Dezvoltarea tehnicilor imagistice a adus o contribuţie importantă în cunoaşterea complexităţii tulburărilor hemodinamicii portale (HDP) generate de afectarea hepatică cronică. Scopul lucrării este evaluarea imagistică eco-Doppler şi analiza comparativă a parametrilor HDP la pacienţii cu ciroză hepatică trataţi chirurgical. Material şi metode: Într-un lot de 111 pacienţi cirotici trataţi chirurgical cu vărsta între 19 şi 47 ani, s-a evaluat gradul de severitate a modificărilor HDP studiat prin ecografie Doppler duplex color cu aprecierea parametrilor cantitativi atât pe versantul arterial, cât şi pe cel venos. Evaluarea severităţii cirozei hepatice a fost apreciată conform clasificării de prognostic Child-Pugh. Rezultate: Preoperator a fost stabilită o corelare importantă a hipersplenismului cu majorarea rezistenţei vasculare la nivelul arterei lienale (r=0,454, Se 79%, Sp 69%, RP +2,5), iar indicele splenoportal a crescut evident paralel cu avansarea sindromului de hipersplenism (r=0,516). Scorul Child corelează puternic cu gradele de severitate a dereglărilor HDP evaluate imagistic. După tratamentul chirurgical se atestă o micşorare a diametrului venei porte şi a fluxului portal, iar fluxul la nivelul arterei hepatice denotă o creştere în paralel cu diminuarea rezistenţei vasculare la acest nivel (p<0,001). Concluzii: Rezultatele obținute prin evaluarea imagistică a HDP trebuie interpretate în context clinic, biologic şi morfologic. Utilizarea unui algoritm care ar asocia parametrii enunţaţi poate reprezenta metoda optimă de stadializare şi monitorizare a tulburărilor HDP.
Introduction: The development of imaging techniques has made an important contribution to knowledge of the complexity of portal haemodynamic (PH) disorders caused by chronic liver disease. The purpose of study was the eco-Doppler imaging assessment and comparative analysis of PH parameters in patients with liver cirrhosis treated surgically. Material and methods: In a group of 111 cirrhotic patients treated surgically with age between 19 and 47 years, the severity of PH disturbances was evaluated by color Doppler duplex ultrasound with quantitative analysis of the characteristics of arterial and venous blood flow. Liver cirrhosis severity was assessed and graded according to Child-Pugh prognostic classification. Results: Preoperative was established significant hypersplenism with increasing of vascular resistance in splenic artery (r=0.454, Se 79%, Sp 69%, RP +2.5) and splenoportal index increase obvious parallel with advancing of hypersplenism syndrome (r=0.516). Child score strongly correlates with the degree of severity of PH disturbances rated by imaging. After surgery there was a reduction in the diameter of the portal vein and portal flow and hepatic artery flow shows an increase in parallel with the decrease of vascular resistance at this level (p<0.001). Conclusions: The results of the imaging assessment of PH must be interpreted in clinical, biological and morphological context. Utilization of an algorithm that can associate above mentioned parameters could optimize the staging and monitoring of PH disorders.
URI: http://repository.usmf.md/handle/20.500.12710/13777
ISSN: 1810-1852
Appears in Collections:Arta Medica Vol. 56 No 3, 2015 ediție specială

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