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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/16667
Title: Principiile chimioterapiei tumorilor maligne
Other Titles: Principles of the chemotherapy of malignant tumors
Authors: Roman, Vladislav
Keywords: malignant tumor;chemotherapy;cytostatic;cancer
Issue Date: 2017
Publisher: Asociația Farmaciștilor din Republica Moldova
Citation: ROMAN, Vladislav. Principiile chimioterapiei tumorilor maligne = Principles of the chemotherapy of malignant tumors. In: Revista Farmaceutică a Moldovei. 2017, nr. 1-2, p. 104. ISSN 1812-5077.
Abstract: Introducere. Cancerul este o problemă de sănătate majoră şi cea mai importantă cauză de deces la nivel mondial, incluzând costuri marcante ale tratamentului antitumoral[l]. La nivel mondial în 2012 au fost înregistrate 14,1 milioane de cazuri noi de cancer, iar 8,2 milioane de persoane au decedat în urma acestei maladii. Scopul lucrării. Cercetareatabloului clinic şiprincipiilor chimioterapiei tumorilor maligne pulmonare. Material şi metode. Analiza şi sinteza reviului literaturii oncologice privind medicaţia tumorilor maligne pulmonare. Rezultate. în cadrul cercetării s-a constatat, că tumorile maligne pulmonare mai frecvent se localizează în lobul superior al pulmonilor (45%), în lobul mijlociu (35%), depăşeau bronhiile şi pulmoni (20%). 65% cazuri au fost diagnosticate în rîndul bărbaţilor, iar 35% cazuri - femeilor. Farmacoterapia s-a efectuat cu chimioterapice citostatice (100%), cu antivomitive (80%), antiinflamatoare steroidiene (75%), diureticele (55%). Majoritatea pacienţilor au dezvoltat complicaţii metastatice (75%). Concluzii. în cadrul cercetării au predominat tumorile maligne ale lobului superior al pulmonilor, fiind tratate cu citostatice şi prin tratament adjuvant şi de susţinere. Eficacitatea metodelor chimioterapice de tratament depinde de tipul, localizarea şi stadiul tumorii. Chimiteorapia poate fi folosită ca singura procedură în tratamentul tumorilor maligne, dar cel mai des, metodele chimioterapice se utilizează în combinaţie cu intervenţiile chirurgicale, radioterapie sau hormonoterapie.
Introduction. Cancer is the major health problem and the most important cause of death worldwide, including outstanding costs of antitumor treatment. [1] In the world, 14,1 million of new cases of cancer have been registered in 2012, and 8,2 million of people died because of this disease. The aim of the study. The study of clinical cases and principles of chemotherapy of malignant lung tumors. Material and methods. The analysis and synthesis of oncological literature on the treatment of malignant lung tumors. Results. During the study it was noted that malignant lung tumors are more often localized in the upper part of the lungs (45%), in the middle part (35%), exceeded the limits of the lungs and bronchi (20%). 65% were diagnosed among men and 35% - among women. The pharmacotherapy was carried out by cytostatic drugs (100%), antiemetics (80%), steroidal anti-inflammatory drugs (75%), diuretics (55%). Most of the patients had metastatic complications (75%). Conclusions. During the study, tumors of the upper lobe of the lungs were more common, being treated with cytostatics, complementary therapy and maintenance therapy. The efficacy of chemotherapy treatment methods depends on the type, location and stage of the tumor. Chemotherapy can be used as a single procedure in the treatment of malignant tumors, but more often, methods of chemotherapy are used in association with surgical methods, radiotherapy and hormone therapy.
metadata.dc.relation.ispartof: Revista Farmaceutică a Moldovei: Materials of First Congress of Pharmaceutical Students Association from Republic of Moldova dedicated to the Year Nicolae Testemitanu "Innovation and creativity in pharmaceutical practice and research”, May 4-7, 2017, Chisinau, Republic of Moldova
URI: http://repository.usmf.md/handle/20.500.12710/16667
ISSN: 1812-5077
Appears in Collections:Revista Farmaceutică a Moldovei Nr. 1-2, 2017

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