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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/1934
Title: Coagulopatia asociată transfuziei masive
Other Titles: Coagulopathy associated massive transfusion
Authors: Cotoban, Nicolae
Plămădeală, Svetlana
Şandru, Serghei
Clim, Alexandru
Condraşov, Alexandru
Issue Date: 2013
Publisher: CEP Medicina
Citation: COTOBAN, Nicolae, PLĂMĂDEALĂ, Svetlana et al. Coagulopatia asociată transfuziei masive. In: Anale Ştiințifice ale IP USMF “Nicolae Testemiţanu”. Ed. a 14-a. Chișinău: CEP Medicina, 2013, vol. 4: Probleme clinico-chirurgicale, pp. 123-127
Abstract: Although massive transfusion is a lifesaving treatment for patients with massive bleeding it itself is responsible for one of the most serious challenges of the patient with acute hemorrhage – coagulopathy. Mechanism of coagulopathy is complex and lethal triad is the starting point that includes acidosis, hypothermia and coagulopathy. In addition to these three factors massive transfusion is responsible for dilution of coagulation factors, dilutional thrombocytopenia and hypocalcaemia. Deşi transfuzia masivă reprezintă colacul de salvare pentru pacienţii cu hemoragii masive ea de una singură este responsabilă de una dintre cele mai grave provocări ale pacientului cu hemoragie acută – coagulopatia. Mecanismul de producere a coagulopatiei este complex şi are ca punct de plecare triada letală, ce include în sine acidoza, hipotermia şi coagulopatia. Pe lângă aceşti 3 factori ai coagulopatiei transfuzia masivă este responsabilă de diluţia factorilor de coagulare, trombocitopenia diluţională şi hipocalcemie.
URI: http://repository.usmf.md/handle/20.500.12710/1934
Appears in Collections:Anesteziologie și reanimatologie

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