- IRMS - Nicolae Testemitanu SUMPh
- 1. COLECȚIA INSTITUȚIONALĂ
- ANALE ȘTIINȚIFICE USMF “NICOLAE TESTEMIȚANU”
- Anale științifice USMF “Nicolae Testemițanu”, 2008, Ediția a IX-a
- Volumul 4
- Traumatologie și ortopedie
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/3372
| Title: | Securitatea oncogenă în cultivarea celulelor stem mesenchimale |
| Other Titles: | The oncogenetic security in mesenchymal stem cells cultivation |
| Authors: | Mocan, Elena
Tagadiuc, Olga
Ciobanu, Pavel
Topor, Boris
Nacu, Viorel |
| Issue Date: | 2008 |
| Publisher: | CEP (Medicina) |
| Citation: | MOCAN, E., TAGADIUC, O. et al. Securitatea oncogenă în cultivarea celulelor stem mesenchimale. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 9-a. Chişinau: СEP Medicina, 2008, Vol. 4: Probleme clinico-chirurgicale, pp. 174-179. |
| Abstract: | The article summarizes recent data concerning developing of the new strategy – genetic instability monitoring techniques in the cultures of human mesenchymal stem cells. Stem cells are characterized by their self-renewal ability and high differentiation potential. Described methods detect cell senescence in culture and evaluate changes associated with moderate telomere shortening and characterized by cell cycle arrest, mutations in genes responsible to apoptosis, and cancer-associated genes p53, p15, Rb, NF-kB, Myc and repair machinery. |
| URI: | http://repository.usmf.md/handle/20.500.12710/3372 |
| Appears in Collections: | Traumatologie și ortopedie
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