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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/4734
Title: Analiza chimico-toxicologică a Carbamazepinei
Other Titles: Chemico-toxicological investigations of carbamazepine
Authors: Rîşcovaia, Mariana
Marcova, Natalia
Cotelea, Tamara
Arama, Efim
Issue Date: 2012
Publisher: CEP "Medicina"
Citation: RÎŞCOVAIA, Mariana, MARCOVA, Natalia, COTELEA, Tamara, ARAMA, Efim. Analiza chimico-toxicologică a carbamazepinei. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 13-a. Chișinău: CEP Medicina, 2012, Vol. 1: Probleme medico-biologice şi farmaceutice, pp. 281-284.
Abstract: We elaborated the TLC method of carbamazepine identification by using three developped systems, specrophotometric method of quantitative determination for carbamazepine in capsule of 0.1g. Using the analytical methods elaborated by us over the artificial test there was extracted carbamazepine from biological liquids (plasma, urine). The output of carbamazepine from plasma was 51.18%; from urine- 43.50% Having considered the elaborated methods as specific and reproductive they are recommended for the study of carbamazepine in biological liquids. A fost elaborată metoda cromatografiei pe strat subţire de identificare a carbamazepinei, utilizând 3 sisteme de solvenţi,metoda spectrofotometrică de dozare în capsule 0,1g. Aplicând metodele analitice elaborate de noi la probele biologice în „vitro” s-a efectuat extracţia carbamazepinei din lichidele biologice. Randamentul carbamazepinei din plasma sanguină este de 51,18%, din urină - 43,50%. Dat fiind faptul, că metodele folosite sunt specifice şi reproductive ele se recomandă pentru studierea carbamazepinei în lichidele biologice.
URI: http://repository.usmf.md/handle/20.500.12710/4734
Appears in Collections:Farmacie. Chimie generală

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