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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/8733
Title: Caracteristica clinico-imunologică a infecţiei respiratorii acute la copilul sub 5 ani, asociată cu infecţia herpetică
Other Titles: Clinico-immunological characteristics of acute respiratory diseases in children under 5 years old, associated with Herpes-infection
Клинико-иммунологическая характеристика острых респираторных заболеваний у детей в возрасте до 5 лет ассоциированные с герпес инфекцией
Authors: Donos, A.
Ţurcan, T.
Gangur, L.
Galupa, L.
Donica-Simco, V.
Iliev, A.
Cobzari, I.
David, A.
Keywords: acute respiratory diseases;herpes virus;immunological disorder
Issue Date: 2012
Publisher: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”
Citation: DONOS, A.; ŢURCAN, T.; GANGUR, L.; DAVID, A.; GALUPA, L.; DONICA-SIMCO, V.; ILIEV, A. Caracteristica clinico-imunologică a infecţiei respiratorii acute la copilul sub 5 ani, asociată cu infecţia herpetică. In: Curierul Medical. 2012, nr. 3(327), pp. 154-156. ISSN 1875-0666.
Abstract: The research group was 47 children under 5 years old with severe respiratory diseases, associated with Herpes-infection. Diagnosis of Herpes-infection was confirmed by PCR and IFM. Immunological disorders were observed in 2/3 cases (decreasing level of CD4, CD8, CD20 and serological fraction IgA and IgG). The presence of HSV and/or CMV in parents was confirmed (PCR – 79%, ELISA – 11%). Viral association (ARD, HSV, CMV) determines immunological disorder and severity of clinical manifestations.
Группа исследования составила 47 детей в возрасте до 5 лет с тяжелыми респираторными заболеваниями, сочетанные с герпес инфекцией. Диагноз герпетической инфекции подтвержден методами ПЦР и ИФМ. Иммунологический дисбаланс отмечен у 2\3 случаев (снижение уровня СД8, СД4, СД20 и сывороточных фракций IgA и IgG). Подтверждено наличие HSV и\или CMV у родителей (методом ПЦР – 79% и ИФА – 11%). Вирусная ассоциация (ОРЗ, HSV, CMV) определяет иммунный дисбаланс и тяжесть клинического течения.
metadata.dc.relation.ispartof: Curierul Medical: Congresul III al Medicilor de Familie din Republica Moldova, 17–18 mai, 2012, Chişinău, Republica Moldova, Conferinţa Naţională „Maladii bronhoobstructive la copii”, consacrată profesorului universitar, doctor habilitat Victor Gheţeul, 27 aprilie, Chişinău, Republica Moldova
URI: http://moldmedjournal.md/wp-content/uploads/2016/09/18.pdf
http://repository.usmf.md/handle/20.500.12710/8733
ISSN: 1875-0666
Appears in Collections:Curierul Medical, 2012, Vol. 327, Nr. 3

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