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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/1176
Title: The predictors of pulmonary tuberculosis in Xpert MBT/Rif positive and resistant assay patients with diabetes mellitus
Authors: Lesnic, Evelina
Malic, Alina
Kulcitkaia, Stela
Niguleanu, Radu
Jucov, Artiom
Gutu-Grecu, Mariana
Cula, Eugenia
Tolmaciov, Mihai
Keywords: tuberculosis;Xpert MBT/Rif;diabetes mellitus
Issue Date: 2018
Publisher: The Scientific Medical Association of the Republic of Moldova
Citation: LESNIC, Evelina, MALIC, Alina, KULCITKAIA, Stela, NIGULEANU, Radu, JUCOV, Artiom, GUTU-GRECU, Mariana, CULA, Eugenia, TOLMACIOV, Mihail. The predictors of pulmonary tuberculosis in Xpert MBT/Rif positive and resistant assay patients with diabetes mellitus. In: The Moldovan Medical Journal. 2018, vol. 61, no 2, pp. 3-8. ISSN 2537-6373.
Abstract: Background: One of the most important among risk factors for active tuberculosis development represents diabetes mellitus. The aim of the study was the assessment of the predictive factors for pulmonary tuberculosis in Xpert MBT/Rif resistant assay patients with diabetes mellitus. Material and methods: A retrospective, selective, descriptive and case-control study was performed. Were enrolled 119 pulmonary drug resistant tuberculosis patients, diagnosed and hospitalized in the Municipal Clinical Hospital of Phthysiopneumology of Chisinau city in the period of 01.01.2013- 01.01.2015. The patients were distributed in 2 groups: the 1st group – 34 MDR-TB patients with diabetes mellitus and the 2nd – 85 MDR-TB patients. Investigations were performed according to the National Clinical Protocol – 123. Results: The biological characteristics of the pulmonary MDR-TB patients with diabetes mellitus were old age with associated diseases, which contributed to a lower treatment outcome. For MDR-TB groups were common social-economic vulnerability, late detection as symptomatic cases and a high treatment success rate. Conclusions: Patients with MDR-TB and diabetes mellitus need an individualized approach for an early TB detection and prompt initiation of the adequate treatment regimen according of the susceptibility testing results.
metadata.dc.relation.ispartof: The Moldovan Medical Journal
URI: http://repository.usmf.md/handle/20.500.12710/1176
https://doi.org/10.5281/zenodo.1299008
http://moldmedjournal.md/wp-content/uploads/2019/01/moldmedjournal-2018-61-2-full-issue.pdf
ISSN: 2537-6373
2537-6381
Appears in Collections:The Moldovan Medical Journal, Vol. 61, No 2, June 2018

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