|
- IRMS - Nicolae Testemitanu SUMPh
- REVISTE MEDICALE NEINSTITUȚIONALE
- The Moldovan Medical Journal
- The Moldovan Medical Journal
- The Moldovan Medical Journal 2018
- The Moldovan Medical Journal, Vol. 61, No 3, October 2018
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/1212
Title: | Tuberculosis evolution and treatment outcome in drug addicted patients |
Authors: | Lesnic, Evelina Cotelea, Eugen |
Keywords: | tuberculosis;drug use;addiction;risk factors |
Issue Date: | 2018 |
Publisher: | The Scientific Medical Association of the Republic of Moldova |
Citation: | LESNIC, Evelina, COTELEA, Eugen. Tuberculosis evolution and treatment outcome in drug addicted patients. In: The Moldovan Medical Journal. 2018, vol. 61, no 3, pp. 15-23. ISSN 2537-6373. |
Abstract: | Background: Drug injection is considered an important issue for the public health of the Republic of Moldova. In the RM the intravenous drug users
(IVDU) are the key population for HIV infection, B and C hepatitis, TB and sexual transmitted diseases. The aim of the study was to assess the tuberculosis
evolution and treatment outcome in intravenous drug addicted patients.
Material and methods: A retrospective selective, descriptive study targeting socioeconomic, demographic, economic and epidemiological peculiarities,
case-management, diagnosis of radiological aspects and microbiological characteristics of 233 patients with pulmonary tuberculosis registered in Chisinau
city from 2012 to 2016 among them 48 IVDU was performed. The results were compared with a sample of 34 IVDU.
Results: Men were predisposed for drug addiction and the age is younger in addicts with tuberculosis. Socioeconomic vulnerability is extended in the
selected groups; however, the poverty deepness was more important in addicted patients with tuberculosis. Close contact with a sick patient predominated
in addicts with tuberculosis, but nobody assessed the contact in addicts without tuberculosis. Associated diseases predominated in addicts with or without
tuberculosis, more frequently were: HIV infected individuals, viral hepatitis and neurological disorders.
Conclusions: Risk factors for tuberculosis in drug addicts were: unemployment and associated lack of health insurance, patient’s homeless state, middle
adulthood and the immune suppressive condition – HIV infection. Major disease-related characteristic in IVDU patients was the presence of severe
destructive forms of tuberculosis and "loss to follow-up" as outcome. |
metadata.dc.relation.ispartof: | The Moldovan Medical Journal |
URI: | http://repository.usmf.md/handle/20.500.12710/1212 https://doi.org/10.5281/zenodo.1456877 http://moldmedjournal.md/wp-content/uploads/2019/01/moldmedjournal-2018-61-3-full-issue.pdf |
ISSN: | 2537-6373 2537-6381 |
Appears in Collections: | The Moldovan Medical Journal, Vol. 61, No 3, October 2018
|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
|