- IRMS - Nicolae Testemitanu SUMPh
- 1. COLECȚIA INSTITUȚIONALĂ
- MedEspera: International Medical Congress for Students and Young Doctors
- MedEspera 2020
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/12294
Title: | The vascularized bone allotransplantation - in a rabbit model, preliminary report |
Authors: | Pavlovschi, Elena Stoian, Alina |
Keywords: | vascularized bone grafts;bone allograft surgical revascularization;angiography |
Issue Date: | 2020 |
Publisher: | MedEspera |
Citation: | PAVLOVSCHI, Elena, STOIAN, Alina. The vascularized bone allotransplantation - in a rabbit model, preliminary report. In: MedEspera: the 8th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2020, pp. 115-116. ISBN 978-9975-151-11-5. |
Abstract: | Introduction. The use of bone transplant has been a successful step in the treatment of a large
number of diseases of the osteoarticular system. But a massive bone defect remains a dilemma
for contemporary reconstructive surgery. Contemporary methods that are used, for the
reconstruction of the bone structure, have a high level of morbidity and complication.
Specialized literature indicates the absence of an optimal solution in massive bone defects
healing. Maintaining the osteoplastic properties of the vascularized autograft; combining them
with the orthotopic characteristics of an allogenic bone would be a successful alternative for
the reconstructive surgery of the skeletal system.
Aim of the study. To determinate the optimal bone segment for allotransplantation and his
sources of vascularization, on the femur in the rabbit model for tissue engineering.
Materials and methods. The study of the vascularization of the femoral bone was performed
on laboratory animals (rabbits). After euthanasia and the femoral bone segment harvesting with
a soft tissue without destroying the vascularization. In the abdominal aorta was injected
contrast material, with the subsequent preparation of the arterial vessels. Followed by
anatomical study, radiography, histology, microangiography of this vascularized bone
segment. Thus we determined the vascularised bone segment which could be used as one graft
for further conservation.
Results. The optimal segment for vascularized allografting (the rabbit model) was the upper
third of the femur with the lateral circumflex femoral artery.
Conclusions. The success after bone vascularized allografting is ensured by keeping the
circulation on arteria nutricia and microcirculation of blood. The vascular living allogeneic
bone without immunosuppression would be a perfect alternative in the treatment of the massive
bone defects. |
URI: | https://medespera.asr.md/wp-content/uploads/ABSTRACT-BOOK.pdf http://repository.usmf.md/handle/20.500.12710/12294 |
ISBN: | ISBN 978-9975-151-11-5. |
Appears in Collections: | MedEspera 2020
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