Abstract: | Introduction: Vegetable oils with lipophilic compounds
(polyunsaturated fatty acids, tocopherols, phytosterols,
carotenoids, organic acids, alcohols, esters, aldehydes,
ketones) and hydrophilic (phenolic acids, aldehydes,
hydroxycinnamic esters, flavonols, procyanidins)
determines a lot of biological properties.
Purpose: Analysis and systematization of the properties
and mechanisms of vegetable oils.
Material and methods: Articles from the PubMed
database were selected and analyzed according to the
keywords „ vegetable oils”,”properties”, “mechanisms”.
Results: Vegetable oils have demonstrated antimicrobial,
antioxidant, anti-inflammatory, anti-tumor, regenerative,
cytoprotective activity. The antioxidant activity is
attributed to scavenging free radicals, inhibited the lipid
peroxidation, decrease the levels of conjugated diene,
malonic dialdehyde, and increase the gene expression
levels and production of some antioxidant enzymes. The
anti-inflammatory activity by inhibited the high nitric
oxide, pro-inflammatory cytokine and prostaglandins,
increase the levels of the cytokines, inhibited inflammatory
cell infiltration and oxidative damage.The anti-tumor effect
involve apoptosis, DNA damage and oxidative stress.
Conclusions: The biological properties of vegetable oils
have been attributed to polyunsaturated fatty acids,
polyphenols, procyanidins, tocopherols, tocotrienols,
carotenoids, phytosterols, chlorophylls, flavonols,
glucoside constituiens. |