Study of sensitivity / resistance of nosocomial strains to disinfectants

Abstract

Introduction. Worldwide, morbidity and mortality of nosocomial infections are on continuous growth, and the causative agents of these infections can remain viable even after exposure to routine disinfectants.Purpose. Determination of resistance /susceptibility of hospital microorganisms to disinfectant solutions. M aterial and methods. It has been studied the sensitivity/resistance of 41 strains of microorganisms to disinfectants from the groups: Oxidants, Alcohols, Aldehyde, QAC (quaternary ammonium compounds), QAC + aldehyde, QAC + amines, Chlorine-containing compounds. The investigated strains were isolated from the patients of the republican-level medical institution. Results. The general sensitivity of the strains to disinfectants was 69.02% and the resistance 30.98%. More resistant disinfectants were Chemiofarm 81.25%, Viruton 64.0%, Smell net 58.53%, vs. more sensitive Peroster 95.12%, Chemiosept 93.75% Gigasept 93.75%, Aseptoman 87.5%, Sterisept 87.09%, Hygiene 85.36%, Dezderman 75.0%, Aniosept 75.0% (Fig.1). The most sensitive groups of disinfectants were Oxidants (83.56%), Alcohols (85.4%), Aldehydes (93.75%), and conversely, more resistant groups QAC 52.18%, QAC + amines 40.0%, Chlorine compounds 37.5%, QAC + aldehydes 34.15% (table 1). Conclusions. The obtained results are necessary for optimization the monitoring of the microorganisms resistance to disinfectant at the level of medical institution, to identify the ineffective solutions.