Disfuncţia tiroidiană asociată cu obezitatea primară la copii şi adolescenţi

Abstract

Over the last decades, obesity is the most common chronic pathology in children and adolescents, affecting each age group. Being a chronic nutritional disorder characterized by the increasing in the body weight due to adipose tissue, obesity is also accompanied by the disruption of obvious links of carbohydrates, lipids and proteins metabolism, and a series of comorbidities. 100 children participating in the research were tested to identify the biochemical and hormonal markers that indicate an obesity related disorder. As a result, it was observed that 27 of the examined children had an increased TSH level (4.7-10 μIU/ml), 2 children had TSH values > 10 μIU/ml, high level of anti-TPO Ab in 14 cases, 65 children presented structural changes of the thyroid. Conclusion: Primary obesity is commonly associated with thyroid dysfunction, particularly subclinical hypothyroidism.