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- IRMS - Nicolae Testemitanu SUMPh
- REVISTE MEDICALE NEINSTITUȚIONALE
- The Moldovan Medical Journal
- The Moldovan Medical Journal
- The Moldovan Medical Journal 2021
- The Moldovan Medical Journal, Vol. 64, No 1, March 2021
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/15882
Title: | Opportunities of Fenspiride anti-inflammatory therapy in patients with chronic obstructive pulmonary disease |
Authors: | Calancea, Valentin Matcovschi, Sergiu Nichita, Svetlana Martiniuc, Constantin |
Keywords: | chronic obstructive pulmonary disease;pulmonary ventilation;exercise tolerance |
Issue Date: | 2021 |
Publisher: | The Scientific Medical Association of the Republic of Moldova |
Citation: | CALANCEA, Valentin, MATCOVSCHI, Sergiu, NICHITA, Svetlana, MARTINIUC, Constantin. Opportunities of Fenspiride anti-inflammatory therapy in patients with chronic obstructive pulmonary disease. In: The Moldovan Medical Journal. 2021, vol. 64, no 1, pp. 22-24. ISSN 2537-6381. DOI: 10.5281/zenodo.4527054 |
Abstract: | Abstract. Background: Currently, bronchodilator medication recommended in the basic treatment of stable chronic obstructive pulmonary disease (COPD) does not have direct anti-inflammatory properties. According to recent researches, Fenspiride has a multi-functional effect on various links of the inflammatory process in the respiratory tract. The purpose of this study was to assess the clinical efficacy and safety of Fenspiride in the treatment of COPD in remission. Material and methods: The research was performed on a group of 42 patients with COPD in stages GOLD 1 and GOLD 2. Depending on the treatment applied, patients were divided into 2 groups. The first group received Fenspiride with basic treatment and the second group only basic treatment. The main symptoms, pulmonary ventilation indexes, and exercise tolerance were assessed in all patients. Results: The results obtained showed that Fenspiride improves the symptoms of the disease, pulmonary ventilation, and increases patients’ exercise tolerance. Conclusions: Fenspiride is an effective and harmless remedy that can be used for the anti-inflammatory treatment of stable COPD in stages GOLD I and II. |
metadata.dc.relation.ispartof: | The Moldovan Medical Journal |
URI: | http://moldmedjournal.md/wp-content/uploads/2021/02/64-1-Mold-Med-Journal-version-3.pdf http://repository.usmf.md/handle/20.500.12710/15882 |
ISSN: | 2537-6381 2537-6373 |
Appears in Collections: | The Moldovan Medical Journal, Vol. 64, No 1, March 2021
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