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- IRMS - Nicolae Testemitanu SUMPh
- REVISTE MEDICALE NEINSTITUȚIONALE
- The Moldovan Medical Journal
- The Moldovan Medical Journal
- The Moldovan Medical Journal 2021
- The Moldovan Medical Journal, Vol. 64, No 1, March 2021
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/16040
Title: | Diagnostic markers of urinary bladder tumors |
Authors: | Vladanov, Ivan Pleșacov, Alexei Colta, Artur Ghicavii, Vitalii |
Keywords: | bladder tumors;tumor markers |
Issue Date: | 2021 |
Publisher: | The Scientific Medical Association of the Republic of Moldova |
Citation: | VLADANOV, Ivan, PLESACOV, Alexei, COLTA, Artur, GHICAVII, Vitalii. Diagnostic markers of urinary bladder tumors. In: The Moldovan Medical Journal. 2021, vol. 64, no 1, pp. 71-75. ISSN 2537-6381. DOI: 10.5281/zenodo.4527239 |
Abstract: | Abstract.
Background: The perfect method for laboratory diagnosis of bladder cancer should have high sensitivity and specificity, should be easily reproducible,
inexpensive, be suitable for primary diagnosis, screening, and follow-up of patients, for timely detection of recurrence. In clinical practice, for bladder
cancer diagnostics have been used the following markers: UBC, BTA, “ImmunoCyt”, NMP22, “UroVision», and others. Each method has relative
advantages and disadvantages. The study has demonstrated an influence on the test result of the histological structure and grade of the tumor, presence
of hematuria, urolithiasis, chronic inflammatory malignancies, recent surgical procedures on the urinary tract. Apparently, the use of a palette of markers
in connection with imaging techniques will increase the diagnostic capabilities, but it is still not clear which elements should be present in such a palette.
Conclusions: At present, basic diagnostic methods for bladder cancer remain: USG, MRI, CT, and endoscopic methods. The laboratory methods that
exist are not informative enough. Each marker has serious restrictions, but possibly the complex application will allow increasing the diagnostic value in
the future, therefore it is necessary to develop new markers of bladder cancer or to study the results of the complex application of several known markers
to increase the value of the laboratory diagnosis of primary bladder cancer and recurrent. |
metadata.dc.relation.ispartof: | The Moldovan Medical Journal |
URI: | http://moldmedjournal.md/wp-content/uploads/2021/03/64-1-0-MMJ-vers-3-martie.pdf http://repository.usmf.md/handle/20.500.12710/16040 |
ISSN: | 2537-6381 2537-6373 |
Appears in Collections: | The Moldovan Medical Journal, Vol. 64, No 1, March 2021
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