Immunological indicators in children with ARF co-associated with herpes infection

Abstract

The objective of the study: Assessing immunological indices in children with acute respiratory infections, serious development, co-associated with herpes infection. Materials and Methods: In the study group were included 100 children with acute respiratory infections, serious development, hospitalized in SCMC PMSI no.1, years 2010-2012. By age patients were divided into 3 groups: 1- children aged of 0-12 months (18,8%), 2- 12-24 months (62,9%),3 - 24-36 months (18,3%). Diagnosis of herpes infection was noted by PCR and enzyme immunoassay. Humoral immunity assessed using the method Mancini, cell immunity with specific monoclonal. All patients included in the study, it was considered positive family epidemiological history at herpes infections. Analysis of the results was performed by the method of medical statistics. Conclusions: 1. Existence of herpetic infections from parents involves a high risk of infection in children. 2. ARF arising on the background of herpes infections is manifested with serious evolution, thanks to immunocompetent cells misbalance, which is manifested by heterogeneous functions and may induce imunopathologies. 3. Reaches a disorder of lymphocyte cytotoxic function TCD4 helper and TCD8 suppressors.