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- IRMS - Nicolae Testemitanu SUMPh
- REVISTE MEDICALE NEINSTITUȚIONALE
- One Health & Risk Management
- One Health & Risk Management 2021
- One Health & Risk Management Vol. 2 No 4, 2021 Supplement
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/18273
Title: | Possible algorithms for determining adverse reactions caused by food supplements in Romania |
Authors: | Matran, Irina Mihaela Muntean, Daniela Lucia Niculas, Cristina Martin-Hadmas, Roxana Maria Tarcea, Monica |
Keywords: | nutrivigilence;algorithms;side effects;health |
Issue Date: | 2021 |
Publisher: | Asociația de Biosiguranță și Biosecuritate din Republica Moldova |
Citation: | MATRAN, Irina Mihaela, MUNTEAN, Daniela Lucia, NICULAS, Cristina, et al. Possible algorithms for determining adverse reactions caused by food supplements in Romania. In: One Health & Risk Management. 2021, vol. 2(suppl.), no 4, p. 22. ISSN 2587-3466. |
Abstract: | Introduction. The advertising of food supplements on various media channels or in specialty stores with natural products and other stores, as well as the lack of informative and
educational programs for the population on side effects and the interaction of food supplements with food and drugs, have led to the development of uncontrolled marketing of
these products. Through this paper we want to present the algorithms that can be applied to determine the side effects caused by food supplements in Romania, the need to
initiate a legislative project on reporting these side effects and educating the population
on the consumption of food supplements.
Material and methods. PubMed, ResearchGate and EUR-Lex databases (online portal
providing access to EU legislation) were analyzed between 2015-2021, based on search
criteria: adverse reactions, ingredient new food, food supplements, algorithms.
Results. Dietary supplements concentrated sources of nutrients or other substances with
a beneficial nutritional or physiological effect intended to supplement a normal diet. They
can be sold as capsules, dragees, tablets, sachets or in bottles. Certain dietary supplements can cause multiple side effects, such as: impaired platelet function by decreased
platelet aggregation, gastrointestinal side effects (diarrhea, vomiting), decreased wound
healing/epithelialization, bacterial or fungal sepsis, most common in patients older.
Probiotics that can cause human sepsis, generally in elderly patients and those suffering
from chronic diseases, are Lactobacilli (strains of L. rhamnosis, due to its high translocation potential), Lactobacillus sp. bacteremia which is sometimes fatal, infectious endocarditis caused by L. rhamnosus, L. casei, L. acidophilus, L. jensenii, L. plantarum and L. paracasei. They can cause anaphylactic response in patients who have undergone cardiovascular surgery or localized infection in diabetes associated with old age and liver transplantation. Side effects have also been found with mineral supplements, omega 3 / fish
oil, soy protein, soy protein, plant nutrients, antioxidants, anti-inflammatory, supplements for weight loss or bodybuilding, various botanical supplements. Multi-skeletal
distortion, fatigue, pain and gastrointestinal symptoms and hepatic adverse events have
been reported with the nutraceutical ingredient RYR (red rice yeast) at the doses recommended by EFSA (European Food Safety Authority). With the exception of "classic"
foods (hazelnuts, nuts, eggs, etc.) known to cause certain side effects such as allergies, the
development of the food industry has led to the emergence of foods eaten especially by
teenagers, such as energy drinks. Frequent consumption of this type of drink was significantly associated with asthma, allergic rhinitis and atopic dermatitis, high stress, lack of
sleep, poor school performance and suicide attempts in Korean adolescents.
Conclusions. It is imperative to legislate the reporting of adverse reactions caused by
food supplements, including their interaction with food or medicine. The veracity of the
practical applicability of the legislation and the existence of an educational program of
the population, make this action not to become null and void. Using the algorithms applied to analyze the severity - causality of adverse reactions caused by drugs, in Romania,
nutrivigilence can be implemented for the health and safety of the population. |
metadata.dc.relation.ispartof: | One Health & Risk Management: The National Scientific Conference with international participation ”ONE HEALTH” approach in a changing world |
URI: | https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/issue/view/17/18 http://repository.usmf.md/handle/20.500.12710/18273 |
ISSN: | 2587-3466 2587-3458 |
Appears in Collections: | One Health & Risk Management Vol. 2 No 4, 2021 Supplement
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