Osteoporosis in men

Abstract

Introduction: Osteoporosis is a disease characterized by low bone mass, deterioration of bone tissue and skeletal fragility consistent with increased risk of fracture. It is a chronic multifactorial disease complex that often develops silently for decades until fractures occur not characteristic. It is shown that there are over 150mln people suffering from this disease. 20% of all osteoporosis cases occur in men. Purpose and Objectives: Clinical-study, indices DXA and FRAX score in men with osteoporosis. Materials and Methods: We performed a study of 40 men> 50 years, hospitalized in Department of Rheumatology and Artrologie of Republican Clinical Hospital. Results: We found that 55 % of men had osteopenia and 45% , osteoporosis. Men using glucocorticoids have a much lower bone density ( T-score -3.1 _ ) than men not receiving glucocorticoids ( T score -1.7 ) . Observed with age and decrease T score so persons aged 50-60 years had the mean T score of -1.9 compared with men aged 60-70 years in the T-score was -2 4 and much higher compared with age > 70 years at the T-score was significantly lower ( - 3.2 ) compared with men with a BMI o f 50-69 ani.Men with BIM <20 T-score was -3, 31 compared with -2.1 at BMI > 20. Men with a rational as> 950 mg / day T-score was -1.75 , and the second group (by rational Like 850- 950m g/zi) T-score was -2.05 . The third group of men who have the smallest rational Ca, about 750- 850 mg / day , are most prone to pathological fracture because their T-score is -3.15 . Male smokers had T-score lower than non-smokers, so the T-score at smokers was -2.64 and non-smokers was -2.36. Conclusions: Osteopoporoza emerged as nosologic unit is very frequently detected in RM even in men of working age. In disease development were presented with high frequency following risk factors: age, smoking, BMI, corticosteroid, intake reduced Ca.