USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/1850
Title: Analiza chimico-toxicologică a alprazolamului
Other Titles: The study of the alprazolam in the chemico-toxicological analyses test
Authors: Cotelea, Tamara
Lungu, Tatiana
Stati, Lilia
Arama, Efim
Issue Date: 2011
Publisher: CEP Medicina
Citation: COTELEA , Tamara, LUNGU, Lilia, STATI, Tatiana, ARAMA, Efim. Analiza chimico-toxicologică a alprazolamului. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 1: Probleme medico-biologice şi farmaceutice, pp. 402-405.
Abstract: There was elaborated the TLC method of alprazolam identification by using of five develop systems, spectrophotometric method of quantitative determination for apprazolam in powder and tablets of 0.001 g were elaborated, as well as HPLC method was elaborated in order to determine the purity of substance.Using the analytical methods elaborated by us over the artificial biological test there was extracted alprazolam from biological liquids (blood plasma, urine). Having considered the elaborated methods as specific and reproductive they a rerecommended for the study of alprazolam in biological liquids. A fost elaborată metoda cromatografiei pe strat subţire de identificare a alprazolamului, utilizând 2 sisteme de solvenţi, metoda spectrofotometrică de dozare în pulbere şi comprimate 0.001 g, precum şi metoda HPLC de identificare în pulbere. Aplicând metodele analitice elaborate de noi la probele biologice „in vitro” s-a efectuat extracţia alprazolamului din lichidele biologice. Dat fiind faptul, că metodele folosite sunt specifice şi reproductive ele se recomandă pentru studierea alprazolamului în lichidle biologice.
URI: http://repository.usmf.md/handle/20.500.12710/1850
Appears in Collections:Chimie generală și farmaceutică. Tehnologia medicamentelor

Files in This Item:
File Description SizeFormat 
ANALIZA_CHIMICO_TOXICOLOGICA_A_ALPRAZOLAMULUI.pdf147.63 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback