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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/23355
Title: Brugada syndrome and job fitness: report of three cases
Authors: Candura, Stefano M.
D’Amato, Luca
Mazzanti, Andrea
Scafa, Fabrizio
Keywords: arrhythmia;sudden cardiac death;electrocardiography;genetic analysis;work fitness
Issue Date: 2022
Publisher: Asociaţia chirurgilor “Nicolae Anestiadi” din Republica Moldov
Citation: CANDURA, Stefano M., D’AMATO, Luca, MAZZANTI, Andrea, SCAFA, Fabrizio. Brugada syndrome and job fitness: report of three cases. In: Arta Medica. 2022, nr. 4(85), p. 135. ISSN 1810-1852.
Abstract: Summary Introduction. Brugada syndrome is an inherited arrhythmogenic disorder predisposing patients to a high risk of sudden cardiac death. Specific guidelines on the health surveillance of affected workers are lacking. Objective. By presenting three illustrative cases, we propose an interdisciplinary approach for the clinical and functional evaluation of Brugada syndrome workers, aimed at continuing the occupational activity, by formulating appropriate prescriptions and limitations. Materials and methods. The subjects were investigated with an interdisciplinary protocol including 24-hour Holter electrocardiography with modified precordial leads, pharmacological test with ajmaline, molecular genetic analysis, electrophysiological study with ventricular stimulation, risk stratification, and occupational medicine evaluation. Results. The first case is a female 42 year-old company manager with positive ajmaline test and CACNA1C gene mutation (judged fit for the job with limitations regarding work-related stress); the second is a male 44 year-old welder with positive ajmaline test, SCN5A gene mutation, and associated OSAS (obstructive sleep apnea syndrome), who was advised to refrain from night shifts and driving company vehicles; the third subject is a male 45 year-old electrical technician with inducible ventricular tachyarrhythmia, who was implanted with a biventricular cardioverter defibrillator, and therefore recommended to avoid exposure to electromagnetic fields and working at heights. Conclusion. Patients with Brugada syndrome may come to the attention of the occupational physician. In this circumstance, the collaboration with an expert cardiologist allows to define the functional capabilities and the arrhythmogenic risk, and to formulate the judgment for job fitness.
metadata.dc.relation.ispartof: Arta Medica: Conferința Națională cu Participare Internațională ”Protecția sănătății - pentru un viitor sigur”, 24-25 noiembrie 2022, Chișinău, Republica Moldova e
URI: https://artamedica.md/index.php/artamedica/issue/view/14/20
http://repository.usmf.md/handle/20.500.12710/23355
ISSN: 1810-1852
1810-1879
Appears in Collections:Arta Medica Nr. 4(85) 2022 ediție specială

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