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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/2899
Title: Renal sympathetic denervation in treatment of patients with resistant arterial hypertension
Other Titles: Desimpatizarea arterelor renale în tratamentul pacienţilor cu hipertensiune arterială rezistentă
Authors: Sapojnic, N.
Moiseeva, A.
Bitca, A.
Caraus, A.
Keywords: renal sympathetic denervation;resistant arterial hypertension
Issue Date: Aug-2014
Publisher: The Scientific Medical Association of the Republic of Moldova
Citation: SAPOJNIC, N., MOISEEVA, A., BITCA, A., CARAUS, A. Renal sympathetic denervation in treatment of patients with resistant arterial hypertension. In: Curierul Medical. 2014, vol. 57, no 4, pp. 67-69. ISSN 1875-0666.
Abstract: Background: Hypertension represents a major health problem and is the most important cause of cardiovascular morbidity and mortality. Despite the plethora of antihypertensive drugs, hypertension remains resistant in a considerable number of patients, thus creating a requirement for alternative strategies, including interventional approaches. Recently, renal sympathetic denervation (RSD) using a very elegant, state-of-the-art technique (percutaneous, catheter-based radiofrequency ablation) has demonstrated its benefit in patients with resistant hypertension. The pathophysiology of kidney function justifies the use of RSD in the treatment of hypertension. Data from previous studies have shown that sympathectomy has efficiently decreased the blood pressure and prolonged the life expectancy of patients with hypertension, but at considerable cost. RSD is devoid of the adverse effects of sympathectomy because of its localized nature, is minimally invasive and provides short procedural and recovery times. The maximum follow-up period is only 3 years, but the beneficial effects of sympathetic denervation of the renal artery on blood pressure, diastolic function and left ventricular remodeling processes, glucose tolerance, insulin resistance and others have already been demonstrated. Conclusions: Renal sympathetic denervation is a promising method in patients with resistant hypertension, but requires additional data from longterm comparative studies to determine certainty of the safety and sustainability of the effects of this procedure compared with optimal medical treatment.
metadata.dc.relation.ispartof: Curierul Medical
URI: http://curierulmedical.org/wp-content/uploads/2016/09/81.pdf
http://repository.usmf.md/handle/20.500.12710/2899
ISSN: 1857-0666
Appears in Collections:Curierul Medical, 2014, Vol. 57, Nr. 4



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