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- IRMS - Nicolae Testemitanu SUMPh
- REVISTE MEDICALE NEINSTITUȚIONALE
- The Moldovan Medical Journal
- Curierul Medical 2009 - 2016
- Curierul Medical, 2014
- Curierul Medical, 2014, Vol. 57, Nr. 4
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/2900
Title: | Riscurile şi conduita sarcinii la pacientele cu proteze valvulare cardiace |
Other Titles: | Risks and pregnancy management in the patients with heart valves prostheses |
Authors: | Cusnir, O. Moscalu, V. Manolache, Gh. Timbalari, A. |
Keywords: | pregnancy;labor;anticoagulant therapy;artificial heart valves |
Issue Date: | 2014 |
Publisher: | Curierul medical |
Citation: | CUSNIR, O., MOSCALU, V., MANOLACHE, Gh., TIMBALARI, A. Risks and pregnancy management in the patients with heart valves prostheses. In: Curierul medical. 2014, nr. 57(4), pp. 69-72. ISSN 1875-0666. |
Abstract: | Background: We have performed a systemic review of the literature to determine pooled estimates of maternal and fetal risks associated with 3
commonly used approaches: 1) the administration of oral anticoagulants throughout the pregnancy, 2) replacing oral anticoagulants with heparin in
the first trimester of the pregnancy, and 3) the administration of heparin throughout the pregnancy. The prenatal care of women with artificial heart
valves remains one of the most complex issues for cardiologists and obstetrician-gynecologists all over the world. Pregnancy and labor of women with
artificial heart valves are usually associated with a high risk. During the pregnancy appears not only the risk of the cardiac pathology progression, but
also of the manifestation of subclinical running hereditary thrombophilia and/ or antiphospholipid syndrome, in the above mentioned case the risk of
thromboembolic episodes pathologies increases manifold. This overview presents the updated data on the ways of administration of anticoagulants that
are most frequently used in the obstetric care. It outlines the principles of the rational anticoagulant therapy during the pregnancy and labor of women
with artificial heart valves, as well as the laboratory monitoring of the performed treatment. The question of the management of pregnant women with
mechanical valve prostheses is quite controversial and there is no universal consensus in this regard. Here there is an increased risk of complications for
both mother and fetus: abortion and placental hemorrhage.
Conclusions: Anticoagulation in pregnant women is individual. Therefore, the therapy strategy should be adequate to ensure a minimum level of
anticoagulation and bleeding complications. |
URI: | http://curierulmedical.org/wp-content/uploads/2016/09/81.pdf http://repository.usmf.md/handle/20.500.12710/2900 |
ISSN: | 1857-0666 |
Appears in Collections: | Curierul Medical, 2014, Vol. 57, Nr. 4
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