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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/3003
Title: Evaluation of antibiotics consumption in therapeutic intensive care department
Authors: Bernaz, Emilian
Keywords: antibiotics;defined daily dose;consumption;rational use;hospitals
Issue Date: 2016
Publisher: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”
Citation: BERNAZ, Emilian. Evaluation of antibiotics consumption in therapeutic intensive care department. In: Curierul Medical. 2016, vol. 59, no 2, pp. 5-10. ISSN 1875-0666.
Abstract: Background: Monitoring of aggregate, ward-supply data and analysis of the anatomical therapeutic chemical/defined daily dose system, adjusted for bed-occupancy, provides a clear picture of antibiotics consumption frequency and time-trends within hospitals and especially intensive care departments. Material and methods: For this study we used data of a five-year (2010-2014) period, in therapeutic intensive care department of the Emergency Medicine Institute, which show the consumption dynamics of anti-infectives for systemic use of drugs in grams and value indexes. Results: The defined daily doses (DDD) per 1000 occupied-bed days (DDD/OBD) of antibiotics in therapeutic intensive care department decreased from 1524 in 2010 to 1206 DDD/1000 in 2014 or by 20.87%, however, it is by 11.77% higher than medium consumption of 1052.25 DDD/1000 in intensive care units with the same activity in international hospitals. The value of 54948 lei per DDD/1000 OBD in 2010 recorded a decline to 40754 lei or by 25.84% in 2014. The cost of one medium DDD from 36.05 lei in 2010 decreased to 33.77 lei or by 6.33% in 2014. The average antibiotics annual institution consumption constituting 464.1 DDD/1000 in 2014 was higher by 1.06% comparatively with medium consumption of 459.20 DDD/1000 registered in 1706 international hospitals, and by 35.31% in comparison with global consumption of 343 defined daily doses per 1000 patient-days. Conclusions: The decrease of DDD/1000 OBD and their cost took place as a result of efforts for rational use of antibiotics during the evaluated period. Great opportunities were found for improving rational utilization of anti-infectives for systemic use.
metadata.dc.relation.ispartof: Curierul Medical
URI: http://curierulmedical.org/wp-content/uploads/2016/09/Cm-2-0-2016-PDF-Integral-3.pdf
http://repository.usmf.md/handle/20.500.12710/3003
ISSN: 1857-0666
Appears in Collections:Curierul Medical, 2016, Vol. 59, No 2

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