USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/30076
Title: Parasitic infestations and their influence on joint inflammation
Authors: Grosu, Maia
Groppa, Liliana
Plăcintă, Gheorghe
Pântea, Victor
Russu, Eugeniu
Keywords: parasitosis;parasitic arthritis;parasitic immune status
Issue Date: 2024
Publisher: Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova
Citation: GROSU, Maia; GROPPA, Liliana; PLĂCINTĂ, Gheorghe; PÂNTEA, Victor; RUSSU, Eugeniu. Parasitic infestations and their influence on joint inflammation. In: Revista de Ştiinţe ale Sănătăţii din Moldova = Moldovan Journal of Health Sciences. 2024, vol. 11, nr. 4, pp. 49-53. ISSN 2345-1467. DOI: https://doi.org/10.52645/MJHS.2024.4.08
Abstract: Objective. The objective of this study was to conduct a bibliographic analysis of current data regarding the impact of parasitic infestations on immune status and the progression of osteoarticular diseases within the context of parasitic infections. Material and methods. This was a qualitative analytical study presented as a narrative literature review. Relevant primary sources published between 2016 and 2022 were identified and selected using data extraction and analysis methods. Results and discussion. The concept of “parasitic therapy” has generated considerable interest among researchers, the public, and patients for whom standard treatments have been ineffective or offered limited results. Although studies exploring the role of parasitic infections in arthritis are less common than in other fields, animal models suggest that parasitic infections may alleviate joint inflammation. However, further research is needed across different forms of arthritis, including clinical data collection and double-blind, controlled clinical trials. Conclusions. While only a few studies have demonstrated that parasitic infections may worsen preexisting diseases, the scientific consensus is that parasitic infections can create an immunoregulatory environment, reducing the severity of coexisting conditions. Finally, more rigorous animal studies are required to thoroughly investigate immunomodulatory mechanisms and potential side effects of parasitic infections in the presence of other diseases.
metadata.dc.relation.ispartof: Revista de Ştiinţe ale Sănătăţii din Moldova = Moldovan Journal of Health Sciences
URI: https://mjhs.md/sites/default/files/2024-12/MJHS_11_4_2024.pdf
http://repository.usmf.md/handle/20.500.12710/30076
https://doi.org/10.52645/MJHS.2024.4.08
ISSN: 2345-1467
Appears in Collections:Revista de Științe ale Sănătății din Moldova : Moldovan Journal of Health Sciences 2024 Vol. 11, Issue 4

Files in This Item:
File Description SizeFormat 
MJHS_11_4_2024_Grosu.pdf832.35 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback