Intervention strategies in acute psychotic disorders: clinical and therapeutic perspectives

Abstract

Acute psychotic disorder is a severe clinical condition with a sudden onset and potentially variable course, requiring early therapeutic intervention to prevent chronicity and optimise functional prognosis. Retrospective analysis of the clinical profile and therapeutic management applied to patients hospitalized with a diagnosis of acute psychotic disorder. Retrospective study on 35 patients with acute psychotic disorder (F23, ICD-10), hospitalized in 2025. Inclusion criteria: acute onset, age between 18 and 50 years. Clinical data were descriptively analysed from medical records. The patients (aged 18–50 years) presented with severe psychomotor agitation, aggressive behavior, auditory hallucinations, and various delusional ideas. Initial treatment consisted of classical injectable antipsychotics and benzodiazepines, used to control agitation and positive symptoms, followed by a switch to second-generation oral antipsychotics (quetiapine, aripiprazole, cariprazine). Hospitalization lasted 15–21 days, and treatment included psychoeducational interventions and psychotherapeutic support. The outcome was favorable. A structured management approach that combines pharmacological interventions with psycho-educational and psychotherapeutic support plays a key role in symptom improvement, recovery, and the prevention of long-term complications.